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The Impact of Early Testicular Sperm Extraction or Cryopreservation on the Outcome of Intracytoplasmic Sperm Injection—A Randomized Controlled Study

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Abstract

Purpose : To compare the outcome of sperm extraction 24 h before ovum pickup and on the day of oocyte retrieval.

Methods : A controlled study was performed to compare the outcome of 90 sperm extractions and in vitro sperm injection cycles performed in 54 patients.

Results : Available fresh sperm for the sperm injection procedure and cryopreservation obtained on the day of ovum pickup were similar to sperm collected 1 day before (33.3% vs. 39.4%, respectively). Fertilization rate obtained with fresh sperm was also similar (48.9% vs. 54%), respectively. Clinical pregnancy rate was 38% vs. 22% per embryo transfer, respectively (P = 0.235). When comparing an additional 24 cycles with cryopreservation of sperm retrieved on the day of ovum pickup, as well as a day previously, no significance was noted in the parameters.

Conclusions : Sperm retrieved 24 h before oocyte retrieval and used as fresh or frozen–thawed for sperm injection are as effective as those used on the day of ovum pickup.

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Dirnfeld, M., Paz, M., Yshai, D. et al. The Impact of Early Testicular Sperm Extraction or Cryopreservation on the Outcome of Intracytoplasmic Sperm Injection—A Randomized Controlled Study. J Assist Reprod Genet 20, 205–209 (2003). https://doi.org/10.1023/A:1024116326465

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  • DOI: https://doi.org/10.1023/A:1024116326465

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