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Effect of Various Factors on the Reaction of 2-Aminobenzothiazoles with Propylene Oxide

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

We have shown that when 2-substituted 2-aminobenzothiazoles react with propylene oxide in proton-donor solvents, products of hydroxyalkylation of both the heterocycle and o-aminothiophenol formed as a result of its cleavage are synthesized. We have traced the effect of the nature of the solvent, various additives, the reaction temperature, and the heating time on this process.

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Authors and Affiliations

  1. Institute of Plant Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent, 700170

    R. F. Ambartsumova & L. P. Kosmacheva

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  1. R. F. Ambartsumova
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  2. L. P. Kosmacheva
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Ambartsumova, R.F., Kosmacheva, L.P. Effect of Various Factors on the Reaction of 2-Aminobenzothiazoles with Propylene Oxide. Chemistry of Heterocyclic Compounds 38, 994–999 (2002). https://doi.org/10.1023/A:1020938001076

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  • DOI: https://doi.org/10.1023/A:1020938001076

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