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Journal of Assisted Reproduction and Genetics

, Volume 16, Issue 9, pp 500–503 | Cite as

Familial Risk Among Patients with Endometriosis

  • Rosana Maria Dos Reis
  • Marcos Felipe Silva De Sá
  • Marcos Dias De Moura
  • Antônio Alberto Nogueira
  • João Ulisses Ribeiro
  • Ester Silveira Ramos
  • Rui Alberto Ferriani
Article

Abstract

Purpose: The objective of the present study was to determine the prevalence of endometriosis among the relatives of patients with confirmed endometriosis.

Methods: We analyzed the prevalence of endometriosis among first-, second-, and third-degree relatives in a group of 101 patients with varying symptoms related to endometriosis seen at two public hospitals and submitted to laparoscopy and/or laparotomy. The control group consisted of 43 women submitted to laparoscopy without a diagnosis of endometriosis.

Results: Among the patients with endometriosis, we detected nine families with a positive history of endometriosis, comprising one mother, six sisters, three aunts, and two cousins, as opposed to no case among the controls.

Conclusions: These data confirm a familial tendency for endometriosis and suggest that this disorder has a genetic basis.

dysmenorrhea endometriosis hereditary disease laparoscopy 

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Copyright information

© Plenum Publishing Corporation 1999

Authors and Affiliations

  • Rosana Maria Dos Reis
    • 1
    • 2
  • Marcos Felipe Silva De Sá
    • 1
  • Marcos Dias De Moura
    • 1
  • Antônio Alberto Nogueira
    • 1
  • João Ulisses Ribeiro
    • 2
  • Ester Silveira Ramos
    • 2
  • Rui Alberto Ferriani
    • 1
  1. 1.Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão PretoUniversity of São PauloBrazil
  2. 2.Mother and Child DepartmentFaculty of Medicine of Trângulo MineiroUberabaBrazil

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