Journal of Assisted Reproduction and Genetics

, Volume 16, Issue 9, pp 492–494 | Cite as

The Ratio of X- and Y-Bearing Sperm in Ejaculates of Men with Three or More Children of the Same Sex

  • Jacquelyn Irving
  • Alan Bittles
  • Joanne Peverall
  • Ashleigh Murch
  • Phillip Matson


Purpose: The present study evaluated the proportions of X-bearing and Y-bearing sperm within the semen of donors who were the declared fathers of three or more sons or daughters.

Methods: The proportions of sperm were determined using dual-color fluorescence in situ hybridization to identify the X and Y chromosomes.

Results:The only difference observed was in semen volume. There was no increase in the proportion of Y-bearing sperm for men with only sons (49.7 ± 1.3%) or of X-bearing sperm for men with only daughters (44.8 ± 2.6%).

Conclusions: A preponderance of either sons or daughters in a family cannot be explained simply by an altered ratio of X-bearing and Y-bearing sperm in the father's semen.

fluorescence in situ hybridization sperm X chromosome Y chromosome 


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Copyright information

© Plenum Publishing Corporation 1999

Authors and Affiliations

  • Jacquelyn Irving
    • 1
  • Alan Bittles
    • 1
  • Joanne Peverall
    • 2
  • Ashleigh Murch
    • 2
  • Phillip Matson
    • 3
  1. 1.Centre for Human GeneticsEdith Cowan UniversityJoondalupWestern Australia
  2. 2.Cytogenetics DepartmentKing Edward Memorial HospitalSubiacoWestern Australia
  3. 3.Concept Fertility CentreKing Edward Memorial HospitalSubiacoWestern Australia

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