Skip to main content
Log in

Ovarian Response to Gonadotropin Stimulation in Repeated IVF Cycles After Unilateral Salpingectomy

  • Published:
Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

Abstract

Purpose : This study aimed to examine ovarian response to gonadotrpoin stimulation after repeated IVF treatment cycles in patients who underwent previous unilateral salpingectomy for tubal pregnancy.

Methods : The study group included 26 patients who underwent unilateral salpingectomy for tubal pregnancy 1–9 years prior to starting IVF treatment. A control group of 52 patients with anatomically intact pelvis was treated during the same time period by ICSI. The two groups were matched for age, number of gonadotropin ampules, and length of stimulation. End point measurements included number of follicles, oocytes, and cleaved embryos in consecutive treatment cycles of each group.

Results : There were 98 cycles in the study group and 154 cycles in the control group. The mean number of follicles, retrieved oocytes, and cleaved embryos were not different in the two groups, and no reductions in these parameters were noted up to 10 cycles of treatment. The mean number of follicles ipsilateral to the operated side was similar to the number of follicles of the contralateral ovary and was not different whether salpingectomy was by laparoscopy or laparotomy.

Conclusions : Unilateral salpingectomy does not affect ipsilateral ovarian response to gonadotropin stimulation even after repeated IVF treatment cycles.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  1. Zeyneloglu HB, Arici A, Olive DL: Adverse effects of hydrosalpinx on pregnancy rates after in vitro fertilization-embryo transfer. Fertil Steril 1998;70(3):492-499

    Google Scholar 

  2. Camus E, Poncelet C, Goffinet F, Wainer B, Merlet F, Nisad I, Philippe HJ: Pregnancy rates after in-vitro fertilization in cases of tubal infertility with and without hydrosalpinx: A meta-analysis of published comparative studies. Hum Reprd 1999;14(5):1243-1249

    Google Scholar 

  3. Strandell A, Lindhard A, Valderstrom U, Thorborn J, Janson PO, Hamberger L: Hydrosalpinx and IVF outcome:Aprospective, randomized multicenter trial in Scandinavia on salpingectomy prior to IVF. Hum Reprod 1999;14(11):2762-2769

    Google Scholar 

  4. Lass A, Ellenbogen A, Croucher C, Trew G, Margara R, Becattini C, Winston RML: Effect of salpingectomy on ovarian response to superovulation in an in vitro fertilization-embryo tranfer program. Fertil Steril 1998;70(6):1035-1038

    Google Scholar 

  5. Romeu A, Steingold K, Jones D, Acosta AA: Significance of bilateral salpingectomy in the outcome of IVF-ET (Abstract p159) Paper presented at fifth World Congress on In Vitro Fertilization and EmbryoTransfer, April 5-10, 1987, Norfolk, VA

  6. Verhulst G, Vandersteen N, Van Steirteghem AC, Devroey P: Bilateral salpingectomy does not compromise ovarian stimulation in an in-vitro fertilization/embryo transfer program. Hum Reprod 1994;9(4):624-628

    Google Scholar 

  7. Dar P, Sachs GS, Strassburger D, Bukovsky I, Arieli S: Ovarian function before and after salpingectomy in artificial reproductive technology patients. Hum Reprod 2000;15(1): 142-144

    Google Scholar 

  8. Strandell A, Lindhard A, Waldenstrom U, Thorburn J: Prophylactic salpingectomy does not impair the ovarian response in IVF treatment. Hum Reprod 2001;16(6):1135-1139

    Google Scholar 

  9. Lass A: What effect does hydrosalpinx have on assisted reproduction? What is the preferred treatment for hydrosalpinges? The ovary’s perspective. Hum Reprod 1999;14(7):1674-1677

    Google Scholar 

  10. Puttemans P, Campo R, Gordts S, Brosens I: Hydrosalpinx and ART. Hydrosalpinx-functional surgery or salpingectomy? Hum Reprod 2000;15(7):1427-1430

    Google Scholar 

  11. Strandell A, Linhard A: Hydrosalpinx and ART: Salpingectomy prior to IVF can be recommended to a well-defined subgroup of patients. Hum Reprod 2000;15(10):2072-2074

    Google Scholar 

  12. Ejdrup Bredkjaer H, Ziebe S, Hamid B, Zhou Y, Loft A, Linhard A, Nyboe Andersen A: Delivery rates after in-vitro fertilization following bilateral salpingectomy due to hydrosalpinges: A case control study. Hum Reprod 1999;14(1):101-105

    Google Scholar 

  13. Beyth Y, Winston RML: Ovum capture and fertility following microsurgical fimbriectomy in the rabbit. Fertil Steril 1981;35(2):464-466

    Google Scholar 

  14. McComb P, Delbeke L: Decreasing the number of ovulations in the rabbit with surgical division of the blood vessels between the fallopian tube and ovary. J ReprodMed 1984;29(5):827-829

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Joseph Tal.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tal, J., Paltieli, Y., Korobotchka, R. et al. Ovarian Response to Gonadotropin Stimulation in Repeated IVF Cycles After Unilateral Salpingectomy. J Assist Reprod Genet 19, 451–455 (2002). https://doi.org/10.1023/A:1020302301326

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1020302301326

Navigation