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4-Hydroxy-2-quinolones. 56. 4-(Adamant-1-yl)thiazolyl-2-amides of 1-R-4-Hydroxy-2-oxoquinoline-3-carboxylic Acids as Potential Antitubercular Agents

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The synthesis, antitubercular, anti-HIV, and antitumor activity of the 4-(adamant-1-yl)thiazolyl-2-amides of 1-R-4-hydroxy-2-oxoquinoline-3-carboxylic acids have been studied. An efficient method for purifying the 4-hydroxy-2-oxoquinoline derivatives from their metal salts is proposed.

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Authors and Affiliations

  1. Ukrainian National Pharmaceutical Academy, Kharkov, 61002

    I. V. Ukrainets, M. Amer, P. A. Bezuglyi, O. V. Gorokhova & L. V. Sidorenko

  2. Taras Shevchenko National University, Kiev, 01030

    A. V. Turov

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  1. I. V. Ukrainets
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  2. M. Amer
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  3. P. A. Bezuglyi
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  4. O. V. Gorokhova
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  5. L. V. Sidorenko
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  6. A. V. Turov
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Ukrainets, I.V., Amer, M., Bezuglyi, P.A. et al. 4-Hydroxy-2-quinolones. 56. 4-(Adamant-1-yl)thiazolyl-2-amides of 1-R-4-Hydroxy-2-oxoquinoline-3-carboxylic Acids as Potential Antitubercular Agents. Chemistry of Heterocyclic Compounds 38, 571–575 (2002). https://doi.org/10.1023/A:1019513313773

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  • DOI: https://doi.org/10.1023/A:1019513313773

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