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Investigation of Nitrogen- and Sulfur-containing Heterocycles. 53. Reactions of 5-Amino-6-mercaptopyrimidines with Derivatives of p-Chloronitrobenzene. Synthesis of a New Heterocyclic System - Pyrimido[4,5-b]-1,4-benzothiazepine

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Abstract

A series of pyrimidyl aryl sulfides was obtained from the reaction of 5-amino-6-mercaptopyrimidines with derivatives of p-chloronitrobenzene containing carbonyl functional groups. The properties of these sulfides and methods of their cyclization into derivatives of a new tricylic system, pyrimido[4,5-b]-1,4-benzothiazepine, were studied.

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REFERENCES

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Authors and Affiliations

  1. Center for the Chemistry of Medicinals, All-Russian Chemical-pharmaceutical Science Research Institute, Moscow, 119815, Russia

    T. S. Safonova, M. P. Nemeryuk, N. A. Grineva & M. M. Likhovidova

  2. Dagestan State University, Makhachkala, 367010, Russia

    M. A. Keremov

Authors
  1. T. S. Safonova
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  2. M. P. Nemeryuk
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  3. N. A. Grineva
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  4. M. A. Keremov
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  5. M. M. Likhovidova
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Safonova, T.S., Nemeryuk, M.P., Grineva, N.A. et al. Investigation of Nitrogen- and Sulfur-containing Heterocycles. 53. Reactions of 5-Amino-6-mercaptopyrimidines with Derivatives of p-Chloronitrobenzene. Synthesis of a New Heterocyclic System - Pyrimido[4,5-b]-1,4-benzothiazepine. Chemistry of Heterocyclic Compounds 37, 245–250 (2001). https://doi.org/10.1023/A:1017531903175

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  • DOI: https://doi.org/10.1023/A:1017531903175

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