Abstract
Purpose: To investigate the relationship between serum prolactin levels in the midluteal phase and the prognosis of pregnancy after IVF-ET.
Methods: Design: Prospective study; Setting: Shimane Medical University Hospital; Patients: 29 patients completing their 34th IVF cycle; and Main outcome measures: Serum levels of prolactin, estradiol-17β, and progesterone in the midluteal phase.
Results: Midluteal prolactin levels were significantly lower in patients with early pregnancy loss than in the successful pregnancy group. The mean progesterone/prolactin ratio and the estradiol-17β/prolactin ratio were highest in patients with early pregnancy loss and were lowest in patients with successful pregnancies.
Conclusions: Findings of this study suggest that measurement of the serum prolactin concentration in the midluteal phase is useful for predicting the outcome of IVF-ET.
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Ozaki, T., Takahashi, K., Kurioka, H. et al. Clinical Assisted Reproduction: Influence of Midluteal Serum Prolactin on Outcome of Pregnancy After IVF-ET: A Preliminary Study. J Assist Reprod Genet 18, 387–390 (2001). https://doi.org/10.1023/A:1016674523317
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DOI: https://doi.org/10.1023/A:1016674523317