Applied Mathematics and Mechanics

, Volume 22, Issue 4, pp 409–424 | Cite as

Computer Simulation of Non-Newtonian Flow and Mass Transport Through Coronary Arterial Stenosis

  • Xin-yu Li
  • Gong-bi Wen
  • Ding Li


A numerical analysis of Newtonian and non-Newtonian flow in an axi-symmetric tube with a local constriction simulating a stenosed artery under steady and pulsatile flow conditions was carried out. Based on these results, the concentration fields of LDL (low-density lipoprotein) and Albumin were discussed. According to the results, in great details the macromolecule transport influences of wall shear stress, non-Newtonian fluid character and the scale of the molecule etc are given. The results of Newtonian fluid flow and non-Newtonian fluid flow, steady flow and pulsatile flow are compared. These investigations can provide much valuable information about the correlation between the flow properties, the macromolecule transport and the development of atherosclerosis.

atherosclerosis non-Newtonian fluid flow macromolecule transport wall shear stress 


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Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • Xin-yu Li
    • 1
  • Gong-bi Wen
    • 1
  • Ding Li
    • 1
  1. 1.Mechanics and Engineering Science DepartmentPeking UniversityBeijingP R China

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