Skip to main content
SpringerLink
Log in

Synthesis of Tetrahydro-1H,7H-benzo[ij]quinolizine-1,7-dione Derivatives

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Tetrahydro-1H,7H-benzo[ij]quinolizine-1,7-diones have been obtained by the cyclization of N-alkoxyphenyl-N-(2-carboxyethyl)-β-alanines. Fission of the ester bond occurs on cyclization of N-(4-ethoxyphenyl)-N-(2-carboxyethyl)-β-alanine, but the cyclization of the 3,4-dialkoxyphenyl derivative leads to the formation of 9-alkoxy-8-hydroxy-2,3,5,7-tetrahydro-1H,7H-benzo[ij]quinolizine-1,7-diones. The corresponding dioximes and diphenylhydrazones were obtained.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. R. K. Hill, in: E. W. Pelletier (ed.), Chemistry of Alkaloids, Van Nostrand Reinhold Co, New York (1970), p. 414.

    Google Scholar 

  2. J. Takagi, T. Nagamatsu, N. Yasuda, H. Kimura, and N. Asahara, Jpn. Patent 63130594; Chem. Abstr., 109, 149342 (1988).

    Google Scholar 

  3. A. F. Bekhli, L. A. Bolotin, and B. V. Lopatin, Khim. Geterotsikl. Soedin., 1390 (1979).

  4. J. R. Merchant and R. B. Upasani, Chem. Ind. (London), 14, 513 (1984).

    Google Scholar 

  5. J. R. Merchant and P. M. Pathare, Indian J. Chem., 26B, 471 (1987).

    Google Scholar 

  6. E. S. Ibrahim, M. O. Orabi, M. El-Badawi, and M. T. Omar, Commun. Fac. Sci. Univ. Ankara, Ser. B: Chem. Engl., 1–2, 39 (1993) (publ. 1995).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Kaunas University of Technology, LT-3028, Kaunas, Lithuania

    K. Kantminene & Z. I. Beresnevicius

  2. Institute of Biochemistry, LT-2600, Vilnius, Lithuania

    G. Mikul'skene

  3. University of Oulu, Linnanmaa, POB 3336, FIN-90571, Oulu, Finland

    O. Hormi

Authors
  1. K. Kantminene
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Mikul'skene
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. O. Hormi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Z. I. Beresnevicius
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kantminene, K., Mikul'skene, G., Hormi, O. et al. Synthesis of Tetrahydro-1H,7H-benzo[ij]quinolizine-1,7-dione Derivatives. Chemistry of Heterocyclic Compounds 38, 422–428 (2002). https://doi.org/10.1023/A:1016027204806

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1016027204806

Search

Navigation