Abstract
4,6,6-Trimethyl-1,4-dihydropyrimidines have been synthesized by condensation of 2-quinazolylguanidines with mesityl oxide. The analogous reaction with benzalacetone leads to unstable 4-methyl-6-phenyl-1,4-dihydropyrimidines, which are oxidized to the corresponding 4-methyl-6-phenylpyrimidines.
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REFERENCES
Kh. S. Shikhaliev, A. V. Falaleev, G. I. Ermolova, and A. S. Solov'ev, Khim. Geterotsikl. Soedin., 934 (1999).
V. P. Maklaev and A. L. Vais, Khim. Geterotsikl. Soedin., 1555 (1975).
W. Wendelien and A. Harler, Monatsh. Chem., 105, 563 (1975).
W. Wendelien and A. Harler, Monatsh. Chem., 106, 1479 (1975).
J. P. Brown, J. Chem. Soc. (C), 1074 (1968).
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Shikhaliev, K.S., Falaleev, A.V., Ermolova, G.I. et al. 2-Quinazolylguanidines in Heterocyclization Reactions. 2. Condensation with α,β-Unsaturated Carbonyl Compounds. Chemistry of Heterocyclic Compounds 38, 210–212 (2002). https://doi.org/10.1023/A:1015395410565
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DOI: https://doi.org/10.1023/A:1015395410565