Abstract
Reaction of 2-(vinyloxy)ethylisothiocyanate with unsaturated carbanions generated in situ from propargyl ethers and amines when treated with superbases, after S-alkylation and cyclization of the adducts in the presence of CuBr, leads to the previously unknown 2,3,5-substituted 1-[2-(vinyloxy)ethyl]pyrroles.
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Brandsma, L., Nedolya, N.A. & Tolmachev, S.V. Development of a Novel Approach to Formation of a Pyrrole Ring: Synthesis of 2,3,5-Substituted 1-[2-(Vinyloxy)ethyl]pyrroles. Chemistry of Heterocyclic Compounds 38, 54–59 (2002). https://doi.org/10.1023/A:1014851208862
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DOI: https://doi.org/10.1023/A:1014851208862