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Adenine and Uracil Derivatives with Antitubercular Activity

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

We have carried out the synthesis and investigated the antitubercular activity of adenine and 5-fluorouracil derivatives. It was found that a comparatively large, lipophilic fragment is needed in the active molecule to inhibit the tuberculosis pathogen.

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Authors and Affiliations

  1. Latvian Institute of Organic Synthesis, Riga, LV-1006

    E. Alksnis, D. Korneeva & E. Lukevics

Authors
  1. E. Alksnis
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  2. D. Korneeva
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  3. E. Lukevics
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Alksnis, E., Korneeva, D. & Lukevics, E. Adenine and Uracil Derivatives with Antitubercular Activity. Chemistry of Heterocyclic Compounds 37, 743–746 (2001). https://doi.org/10.1023/A:1011973514672

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  • DOI: https://doi.org/10.1023/A:1011973514672

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