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Heterocyclization of Derivatives of 4-Oxoalkanoic Acids to 1,5-Disubstituted Pyrrolin-2-ones

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Abstract

Conditions were developed for the synthesis and production of 1-aryl-5-alkyl(aryl)-3H- and 1-aryl-5-alkyl(aryl)-5H-pyrrolin-2-ones from the amides and esters of 4-oxoalkanoic acids. It was established that the yield and ratio of the 3H and 5H isomers depend on the substrate employed in the reaction.

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Authors and Affiliations

  1. N. G. Chernyshevskii Saratov State University, Saratov, Russia

    A. Yu. Egorova, V. A. Sedavkina & Z. Yu. Timofeeva

Authors
  1. A. Yu. Egorova
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  2. V. A. Sedavkina
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  3. Z. Yu. Timofeeva
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Egorova, A.Y., Sedavkina, V.A. & Timofeeva, Z.Y. Heterocyclization of Derivatives of 4-Oxoalkanoic Acids to 1,5-Disubstituted Pyrrolin-2-ones. Chemistry of Heterocyclic Compounds 37, 694–697 (2001). https://doi.org/10.1023/A:1011957011038

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  • DOI: https://doi.org/10.1023/A:1011957011038

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