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ZTTA, a Prolyl Endopeptidase Inhibitor, Potentiates the Arginine-Vasopressin-Induced Incorporation of [14C]Leucine in Rat Amygdaloid and Cortical Slices

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REFERENCES

  1. G. F. Koob, C. Lebrun, R. M. Bluthe, R. Dantzer, and M. Le Moal, Role of neuropeptides in learning versus performance: focus on vasopressin. Brain Res. Bull. 23:359-364 (1989).

    Google Scholar 

  2. E. Fliers, G. J. De Vries, and D. F. Swaab. Changes with aging in the vasopressin and oxytocin innervation of the rat brain. Brain Res. 348:1-8 (1985).

    Google Scholar 

  3. T. Araki, H. Kato, T. Inoue, and K. Kogure. Regional impairment of protein synthesis following brief cerebral ischemia in the gerbil. Acta Neuropathol. 79:501-505 (1990).

    Google Scholar 

  4. A. S. Fleming, U. S. Cheung, and M. Barry. Cycloheximide blocks the retention of maternal experience in postpartum rats. Behav. Neural Biol. 53:64-73 (1990).

    Google Scholar 

  5. S. Shibata, T. Hamada, K. Tominaga, and S. Watanabe. An in vitro circadian rhythm of protein synthesis in the rat suprachiasmatic nucleus under tissue cultured condition. Brain Res. 584:251-256 (1992).

    Google Scholar 

  6. S. Feig and P. Lipton. Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism. J. Neurosci. 13:1010-1021 (1993).

    Google Scholar 

  7. Y. Shishido, M. Furushiro, S. Tanabe, S. Nishiyama, S. Hashimoto, M. Ohno, T. Yamamoto, and S. Watanabe. ZTTA, a post proline cleaving enzyme inhibitor, improves cerebral ischemia-induced deficits in a three-panel runway task in rats. Pharmacol. Biochem. Behav. 55:333-338 (1996).

    Google Scholar 

  8. Y. Shishido, M. Furushiro, S. Tanabe, A. Taniguchi, S. Hashimoto, T. Yokokura, S. Shibata, T. Yamamoto, and S. Watanabe. Effect of ZTTA, a prolyl endopeptidase inhibitor, on memory impairment in a passive avoidance test of rats with basal forebrain lesions. Pharm. Res. 15:1908-1911 (1998).

    Google Scholar 

  9. G. Banker and C. W. Cotman. Characteristics of different amino acids as protein precursors in mouse brain: advantages of certain carboxyl-labeled amino acids. Arch. Biochem. Biophys. 142:565-573 (1971).

    Google Scholar 

  10. J. J. Vornov and J. T. Coyle. Glutamate neurotoxicity and the inhibition of protein synthesis in the hippocampal slice. J. Neurochem. 56:996-1006 (1991).

    Google Scholar 

  11. M. Muhlethaler, J. J. Dreifuss, and B. H. Gahwiler. Vasopressin excites hippocampal neurons. Nature 296:749-751 (1982).

    Google Scholar 

  12. R. E. Brinton and B. S. McEwen. Vasopressin neuromodulation in the hippocampus. J. Neurosci. 9:752-759 (1989).

    Google Scholar 

  13. N. Miura, S. Shibata, and S. Watanabe. Increase in the septal vasopressin content by prolylendopeptidase inhibitors in rats. Neurosci. Lett. 196:128-130 (1995).

    Google Scholar 

  14. G. L. Kovacs, B. Bohus, D. H. G. Versteeg, E. R. De Kloet, and D. De Wied. Effect of oxytocin and vasopressin on memory consolidation: sites of action and catecholaminergic correlates after local microinjection into limbic-midbrain structures. Brain Res. 175:303-314 (1979).

    Google Scholar 

  15. T. Yoshimoto, K. Kado, F. Matsubara, N. Koriyama, H. Kaneto, and D. Tsuru. Specific inhibitor for prolyl endopeptidase and their anti-amnesic effect. J. Pharmacobiodyn. 10:730-735 (1987).

    Google Scholar 

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Author notes

  1. Yoshiyuki Shishido

    Present address: Yakult Central Institute for Microbiological Research, 1796, Yaho, Kunitachi-shi, Tokyo, 186-8650, Japan

  2. Shigenobu Shibata

    Present address: Department of Pharmacology, School of Human Sciences, Waseda University, Tokorozawa-shi, Saitama, 359-1192, Japan

Authors and Affiliations

  1. Department of Pharmacology, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan

    Yoshiyuki Shishido, Takeshi Tanaka, Shigenobu Shibata & Shigenori Watanabe

  2. Yakult Central Institute for Microbiological Research, Japan

    Shuichi Tanabe, Masayoshi Furushiro, Shusuke Hashimoto & Teruo Yokokura

Authors
  1. Yoshiyuki Shishido
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  2. Takeshi Tanaka
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  3. Shuichi Tanabe
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  4. Masayoshi Furushiro
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  5. Shusuke Hashimoto
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  6. Teruo Yokokura
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  7. Shigenobu Shibata
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  8. Shigenori Watanabe
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Corresponding author

Correspondence to Yoshiyuki Shishido.

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Shishido, Y., Tanaka, T., Tanabe, S. et al. ZTTA, a Prolyl Endopeptidase Inhibitor, Potentiates the Arginine-Vasopressin-Induced Incorporation of [14C]Leucine in Rat Amygdaloid and Cortical Slices. Pharm Res 16, 463–465 (1999). https://doi.org/10.1023/A:1011946323792

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