Abstract
Purpose: The purpose was to determine whether the number of embryos available for transfer following IVF in women over age 39 predicted a successful pregnancy outcome.
Methods: Retrospective analysis of 455 consecutive IVF cycles in women ≥ years of age.
Results: Few cycles were canceled (29/455, 6.4%) or produced no embryos (5/455, 1.1%). Women 40–43 years of age with normal ovarian reserve had a significantly greater delivery rate when ≥4 embryos were available for transfer than when <4 embryos were available (17.8% versus 2.4%, P = 0.002). Subsequent IVF cycles, from women with normal FSH whose first cycle produced <4 embryos, produced delivery rates of 13.0% when ≥4 embryos were available. Women with abnormal ovarian reserve or age ≥44 years had very low delivery rates (1.2% and 1.4% respectively).
Conclusions: The number of embryos available for transfer significantly predicts delivery from IVF–ET among reproductively older women. Many women age 40–43 with normal ovarian reserve can achieve pregnancy through IVF.
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Opsahl, M.S., Blauer, K.L., Black, S.H. et al. Clinical Assisted Reproduction: The Number of Embryos Available for Transfer Predicts Successful Pregnancy Outcome in Women over 39 Years with Normal Ovarian Hormonal Reserve Testing. J Assist Reprod Genet 18, 551–556 (2001). https://doi.org/10.1023/A:1011906024170
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DOI: https://doi.org/10.1023/A:1011906024170