Abstract
The use of systemic antibacterial drugs in Bulgaria for the period from 1979 to 1994 had been studied using the Defined Daily Doses (DDD) methodology. The total consumption of antibacterials, the consumption by therapeutic groups and preparations were presented. The usage of anti‐infectives in Bulgaria was growing during the period under discussion. Most of the groups followed the general tendency of the total consumption showing their own variations throughout the years. The role of the different preparations was defined. Bulgarians' way of using antibacterials showed the following characteristics: permanent increase in the total consumption; high consumption of tetracyclines and extended spectrum penicillins: low consumption of narrow spectrum antibiotics; and relatively high consumption of aminoglycosides and chloramphenicol, In this study an attempt was made to relate the data with several factors influencing the consumption. For comparison we studied available statistical data of some other countries.
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References
WHO‐Systems of classification for pharmaceuticals (ATC) and for Defined Daily Doses (DDD), Report on the second consultation, Oslo, 1990.
WHO‐Third consultation on systems of classification for pharmaceuticals and for Defined Daily Doses, Oslo, 1991.
Hays R, Cooper C, Bridges‐Webb C. Antibiotics in acute respiratory infections. Med J Aust. 1993;158:691‐6.
Kunin C. Rational use of antibiotics, WHO Drug Information 1990;4:4‐7.
WHO Collaborating Centre for Drug Statistics Methodology Guidelines for DDD, Oslo, 1993.
Manus M. Drug utilization. Med J Aust 1993;158:724.
Birkett D, Michell S, Godesk A, Grigson T, Cully R, Lee C. Profiles of antibacterial drugs use in Australia and trends from 1987 to 1989. Med J Aust 1991;155:410‐5.
Tabulet F. Presentation d'une methodologie permettant de mesurer en quantité et de comparer les consommations pharmaceutiques. Journal d'Economie Medicale T.8n 1990;1:37‐63.
Drug utilisation in Norway during the 1970s–increases, inequalities, innovations, Norwegian Medicinal Depot, Oslo, 1983.
Legemiddelforbruket i Norge 1984‐1988 (Statistics on medicines of Norway) Norsk Medicinaldepot, Oslo, 1989.
Legemiddelforbruket i Norge 1989‐1992 (Statistics on medicines of Norway) Norsk Medicinaldepot, Oslo, 1993.
Kiivet RA, Bergman U, Sjoqvist F. The use of drugs in Estonia as compared to the Nordic countries. Eur J Clin. Pharmacol 1992;42:511‐5.
Kiivet RA, Biba V, Enache D, Foltan V, Gulbinovich J, Oltvayi N, Orazem A, Popova M, Stica L. Changes in the use of anti‐bacterial drugs in the countries of central and Eastern Europe. Eur. J Clin. Pharmacol 1995;48:299‐304.
Sigfusson E. Healthy people and low drug consumption in Aland Islands; News on statistics–2/94 supplement, 1994.
Edmonds D, Dumbrell D, Primrose J, McManus P, Birkett D, Demirian V. Development of an Australian Drug Utilization Database, Pharmaco Economics 1993;3(6):427‐32.
Birkett D. Monitoring drug use in Australia. Australian Prescriber 1993;116:27‐9.
Markova B. Analysis of the resistance of pathogenic microorganisms in terms of optimising the antibacterial therapy. Information bulletin Medical Faculty, Sofia, 1994.
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Popova, M., Guencheva, G. Consumption of anti‐infective drugs in Bulgaria for the period from 1979 to 1994.. Pharm World Sci 19, 93–100 (1997). https://doi.org/10.1023/A:1008636908431
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DOI: https://doi.org/10.1023/A:1008636908431