Skip to main content
SpringerLink
Log in

Phase II Study of Pyrazoloacridine in Metastatic Renal Cell Carcinoma

  • Published:
Investigational New Drugs Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

REFERENCES

  1. Adjei AA, Charron M, Rowinsky EK, Svingen PA, Miller J, Reid JM, Sebolt-Leopold J, Ames MM, Kaufman SH:Effect of pyrazoloacridine (NSC 366140) on DNA topoisomerases I and II.Clin Cancer Res 4:683–691,1998

    Google Scholar 

  2. Sebolt JS, Scavone SV, Pinter CD, Hamelehle KI, VonHoff DD, Jackson RC: Pyrazoloacridines, a new class of anticancer agents with selectivity against solid tumors in vitro.Cancer Res 47:4299–4304,1987

    Google Scholar 

  3. LoRusso P, Wozniak AJ, Polin L, Capps D, Leopold WR, Werbel LM, Biernat L, Dan ME, Corbett TH: Antitumor efficacy of PD115934 (NSC 366140) against solid tumors of mice.Cancer Res50: 4900–4905,1990

    Google Scholar 

  4. Rowinsky EK, Noe DA, Grochow LB, Sartorious SE, Bowling MK, Chen TL, Lubejko BG, Kaufmann SH, Donehower RC: Phase I and pharmacologic studies of Pyrazoloacridine, a novel DNA intercalating agent, on single-dosing and multiple-dosing schedules.J Clin Onc13:1975–1984,1995

    Google Scholar 

  5. National Cancer Institute: Investigator's Handbook: A manual for participants in clinical trials of investigational agents sponsored by DCTD, NCI.Bethesda, MD. National Cancer Institute,1993

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Grant/Riverside Hospital, Columbus, OH, U.S.A.

    J. Philip Kuebler & Timothy Moore

  2. Cancer Center of the Carolinas, Greenville, South Carolina, U.S.A.

    Gerald W. King

  3. The James Cancer Center, Columbus, OH, U.S.A.

    Pierre Triozzi & Eric H. Kraut

Authors
  1. J. Philip Kuebler
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gerald W. King
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Pierre Triozzi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Timothy Moore
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Eric H. Kraut
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kuebler, J.P., King, G.W., Triozzi, P. et al. Phase II Study of Pyrazoloacridine in Metastatic Renal Cell Carcinoma. Invest New Drugs 19, 327–328 (2001). https://doi.org/10.1023/A:1010622129173

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1010622129173

Keywords

Search

Navigation