Pharmacy World and Science

, Volume 26, Issue 1, pp 6–7 | Cite as

Massive nasal bleeding and hemodynamic instability associated with clopidogrel

  • Flávio E. Nácul
  • Emanuela de Moraes
  • Carmen Penido
  • Roberto B. Paiva
  • João G.C. Méier-Neto


A 58-year-old woman was brought to our emergency department with massive nasal bleeding and hemodynamic instability. The patient had been on clopidogrel treatment (75 mg/day) for 2 years, which was started after an episode of transitory ischemic attack. Blood pressure normalized following the administration of intravenous fluids, and the bleeding stopped after nasal tamponade and desmopressin therapy.

Clopidogrel Epistaxis Hemodynamic instability Nasal bleeding 


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Copyright information

© Kluwer Academic Publishers 2004

Authors and Affiliations

  • Flávio E. Nácul
    • 1
  • Emanuela de Moraes
    • 1
  • Carmen Penido
    • 1
  • Roberto B. Paiva
    • 1
  • João G.C. Méier-Neto
    • 1
  1. 1.Clinical Research Center & Intensive Care MedicineClínica São VicenteRio de JaneiroBrazil

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