Advertisement

Journal of Radioanalytical and Nuclear Chemistry

, Volume 249, Issue 2, pp 429–435 | Cite as

Long-term selenium status in humans

  • C. K. Baskett
  • V. L. Spate
  • M. M. Mason
  • T. A. Nichols
  • A. Williams
  • I. M. Dubman
  • A. Gudino
  • J. Denison
  • J.S. MorrisEmail author
Article

Abstract

The association of sub-optimal selenium status with increased riskfactors for some cancers has been reported in two recent epidemiological studies.In both studies the same threshold in selenium status was observed, belowwhich, cancer incidence increased. To assess the use of nails as a biologicmonitor to measure the long-term selenium status, an eight-year longitudinalstudy was undertaken with a group of 11 adult subjects, 5 women and 6 men.Selenium has been measured by instrumental neutron activation analysis. Differencesbetween fingernails and toenails will be discussed. In addition, the resultswill be discussed in the context of the long-term stability of the nail monitorto measure selenium status during those periods when selenium determinantsare static; and the changes that occur as a result of selenium supplementation.

Keywords

Physical Chemistry Inorganic Chemistry Selenium Activation Analysis Cancer Incidence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    M. P. Rayman, B. M. J., (1997) 8 Feb.Google Scholar
  2. 2.
    D. H. Holben,A. M. Smith, J. Amer. Diet. Assoc., 99 (1999) No. 7, 836.CrossRefGoogle Scholar
  3. 3.
    D. J. Hunter,J. S. Morris,C. G. Chute,E. Kushner,G. A. Colditz,M. J. Stampfer,F. E. Speizer,W. C. Willett, Amer. J. Epidemiol., 132 (1990) No. 1, 114.CrossRefGoogle Scholar
  4. 4.
    M.-L. Ovaskainen,J. Virtamo,G. Alfthan,J. Haukka,P. Pietinen,P. R. Taylor,J. K. Huttunen, Am. J. Clin. Nutr., 57 (1993) 662.CrossRefGoogle Scholar
  5. 5.
    H. E. Ganther, Carcinogenesis, 20 (1999) No. 9, 1657.CrossRefGoogle Scholar
  6. 6.
    G. F. Combs, Jr.,W. P. Gray, Pharmacol. Ther., 79 (1998) No. 3, 179.CrossRefGoogle Scholar
  7. 7.
    L. C. Clark,G. F. Combs, Jr.,B. W. Turnbull,E. H. Slate,D. K. Chalker,J. Chow,L. S. Davis,R. A. Glover,G. F. Graham,E. G. Gross,A. Krongrad,J. L. Lesher,H. K. Park,B. B. Sanders, Jr.,C. L. Smith,J. R. Taylor, J. A. M. A., 276 (1996) 1957.CrossRefGoogle Scholar
  8. 8.
    L. C. Clark,B. Dalkin,A. Krongrad,G. F. Combs, Jr.,B. W. Turnbull,E. H. Slate,R. Witherington,J. H. Herlong,E. Janosko,D. Carpenter,C. Borosso,S. Falk,J. Rounder, Br. J. Urology, 81 (1998) 730.CrossRefGoogle Scholar
  9. 9.
    K. Yoshizawa,W. C. Willett,J. S. Morris,M. J. Stampfer,D. Spiegelman,E. B. Rimm,E. Giovannucci, J. Nat. Canc. Inst., 90 (1998) No. 16, 1219.CrossRefGoogle Scholar
  10. 10.
    P. R. Taylor,D. Albanes, J. Nat. Canc. Inst., 90 (1998) No. 16, 1184.CrossRefGoogle Scholar
  11. 11.
    J. Virtamo,E. Valkeila,G. Alfthan,S. Punsar,J. K. Huttunen,M. J. Karvonen, Am. J. Epidemiol., 122 (1985) 276.CrossRefGoogle Scholar
  12. 12.
    S. Salvini,D. Diet,C. H. Hennekens,J. S. Morris,W. C. Willett,M. J. Stampfer, Am. J. Cardiol., 76 (1995) 1218.CrossRefGoogle Scholar
  13. 13.
    M. Navarro-Alarcon,H. Lopez-Garcia de la Serrana,V. Perez-Valero,C. Lopez-Martinez, Ann. Nutr. Metab., 43 (1999) 30.CrossRefGoogle Scholar
  14. 14.
    P. Suadicani,H. O. Hein,F. Gyntelberg, Athero., 96 (1992) 33.CrossRefGoogle Scholar
  15. 15.
    K. Ge,G. Yang, Am. J. Clin. Nutr. Suppl., 57 (1993) 259S.CrossRefGoogle Scholar
  16. 16.
    R. D. Utiger, N. Engl. J. Med., 339 (1998) No. 16, 1156.CrossRefGoogle Scholar
  17. 17.
    M. A. Beck, Nutr. Rev., 56 (1998) No. 1, S140.CrossRefGoogle Scholar
  18. 18.
    C. Allavena,B. Dousset,T. May,F. Dubois,P. Canton,F. Belleville, Biol. Tr. El. Res., 47 (1995) 133.CrossRefGoogle Scholar
  19. 19.
    A. Cirelli,M. Ciardi,C. D. Simone,F. Sorice,R. Giordano,L. Ciaralli,S. Costantini, Clin. Biochem., 24 (1991) 211.CrossRefGoogle Scholar
  20. 20.
    C. K. Baskett,J. S. Morris,V. L. Spate,M. M. Mason,T. P. Cheng,T. A. Nichols,H. D. Anderson,C. J. Tharp,T. Horsman,R. P. Dowdy, J. Radioanal. Nucl. Chem., 236f (1998) 39.CrossRefGoogle Scholar
  21. 21.
    C. K. Baskett,V. L. Spate,J. S. Morris,H. D. Anderson,M. M. Mason,C. L. Reams,T. P. Cheng,K. R. Zinn,G. M. Hill,R. P. Dowdy, J. Radioanal. Nucl. Chem., 195 (1995) 97.CrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers/Akadémiai Kiadó 2001

Authors and Affiliations

  • C. K. Baskett
    • 1
  • V. L. Spate
    • 1
  • M. M. Mason
    • 1
  • T. A. Nichols
    • 1
  • A. Williams
    • 1
  • I. M. Dubman
    • 1
  • A. Gudino
    • 1
  • J. Denison
    • 1
  • J.S. Morris
    • 1
    Email author
  1. 1.Research Reactor CenterUniversity of Missouri-ColumbiaColumbiaUSA

Personalised recommendations