Pharmacy World and Science

, Volume 23, Issue 5, pp 181–182 | Cite as

The incidence and reporting of adverse drug reactions in the Division of Psychiatry

  • P. Brown
  • L. Faloon


Objective: to determine the incidence, severity and reporting of adverse drug reactions occurring to newly marketed drug (all drugs annotated with a black triangle symbol) in the Division of Psychiatry.

Method: all patient commenced on a black triangle drug in the previous month and satisfying all inclusion criteria were interviewed by a pre‐registration pharmacist. The investigator collected details regarding drug prescribed, side effects reported and non‐compliance. Reports sent to the CSM were noted.

Results: Twenty‐two patients received 25 black triangle drugs. Sixteen (60%) suffered an adverse drug reaction. Eight reported these to their doctor with 7 (28%) discontinuing treatment due to the severity of the side effects. Two adverse drugs reactions were classified as serious according to CSM criteria (jerking movements, rash), 3 further reactions led to a deterioration in the patients mental state. No yellow cards were completed.

Conclusion: both patient and health care professionals underreport adverse drug reactions. All reactions to a black triangle drug should be reported. A medicines and healthy living group attended by patients and professionals involved in their case has allowed an increased awareness, monitoring and reporting of adverse drug reactions.

Drugs reactions Side effects Triangle drug 


  1. 1.
    Medicines Evaluation Group, Centre for Health Economics, University of York. The Management of Schizophrenia. Part 1. Pharmacological treatments. Royal College of Psychiatrists Research Unit. 07/06/2000Google Scholar
  2. 2.
    Knapp M. Costs of Schizophrenia. Br J Psychiatry 1997; 171:509-18.Google Scholar

Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • P. Brown
    • 1
  • L. Faloon
    • 2
  1. 1.Department of PsychiatryManchester Royal InfirmaryManchesterUK
  2. 2.Department of PharmacyWithington HospitalManchesterUK

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