Pharmacy World and Science

, Volume 22, Issue 4, pp 152–158 | Cite as

Rational pharmacotherapy and clinical practice guidelines Theories and perspectives on implementing pharmacotherapeutic treatment guidelines

  • R. Fijn
  • J.R.B.J. Brouwers
  • J.W. Timmer
  • L.T.W. de jong-van den berg


Several theories behind implementing clinical guidelines have been described within the literature. At first sight, these may seem different. However, there are similarities and eventually they are rather complementary than mutually exclusive. This article integrates several theoretical views on implementation of pharmacotherapeutic treatment guidelines and subsequently addresses some empirical considerations. Furthermore, specific limitations and potential harms of implementating guidelines are addressed. Several checklists are provided in order to make pharmacists, pharmacologists and clinicians aware of perspectives on dissemination, implementation, and subsequent application of pharmacotherapeutic treatment guidelines.

Bandura's social cognitive theory Clinical practice guidelines (CPGs) Dissemination Fox' barriers to adoption Healthcare model of change Implementation Pathman's awareness‐to‐adherence model Pharmacotherapeutic treatment guidelines (PTGs) Rogers' innovation‐diffusion theory 


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Copyright information

© Kluwer Academic Publishers 2000

Authors and Affiliations

  • R. Fijn
    • 1
  • J.R.B.J. Brouwers
    • 2
  • J.W. Timmer
    • 2
  • L.T.W. de jong-van den berg
    • 2
  1. 1.Department of Social Pharmacy and PharmacoepidemiologyGroningen University Institute for Drug Exploration (GUIDE), University of GroningenGroningenThe Netherlands
  2. 2.Department of Social Pharmacy and PharmacoepidemiologyGroningen University Institute for Drug Exploration (GUIDE), University of GroningenGroningenThe Netherlands

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