Pharmacy World and Science

, Volume 19, Issue 2, pp 60–69 | Cite as

Antiepileptic drug treatment in the nineties in The Netherlands.

  • D.G.A. Kasteleijn‐Nolst TrenitÄ
  • P.M. Edelbroek


In this review the ‘state of the art’ of treating patients with epilepsy in the nineties in the Netherlands is presented. It describes general strategies for treatment with antiepileptic drugs and the history of development of the classical anticonvulsant drugs. Eight new drugs, including vigabatrin, lamotrigine, felbamate, oxcarbazepine, gabapentin, tiagabine, levetiracetam and topiramate are discussed. A review of their pharmacological and clinical properties is presented. Dutch experience with these drugs is included.

Epilepsy treatment Antiepileptic drugs Pharmacology Pharmacokinetics Vigabatrin Lamotrigine Felbamate Oxcarbazepine Gabapentin Tiagabine Levetiracetam Topiramate 


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Copyright information

© Kluwer Academic Publishers 1997

Authors and Affiliations

  • D.G.A. Kasteleijn‐Nolst TrenitÄ
    • 1
  • P.M. Edelbroek
    • 1
  1. 1.Instituut voor EpilepsiebestrijdingHeemstedeThe Netherlands

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