Discussion of the AED workshop.
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An overview is given of the different issues that have been discussed, with subsequent recommendation. Standardisation of measurement and reporting of eficacy parameter and side-effects is essential; not only the number of patients achieving complete seizure controlled or have a decrease in seizure frequency and severity should be mentioned but also the number who dropped out and the reasons therefore. More information is neede on the teratogeneticy of a drug, either by performing control trials or by registration of all pregnancies with new anti‐epileptic drugs. Appropriate bio‐marker for efficacy and toxicity should be developed. Health-related quality of life scales, collecting both subjective and objective information should be developed and used as complimentary tools in understanding more about the disease. A drug that improves the quality of life but is less effective in suppressing seizures should be marketed. Finally, pharmaco‐economic studies should be encuraged in the field of epilepsy.
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