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Interacting Factors in the Epidemiology of Trypanosomiasis in an Endemic/Enzootic Region of Uganda and its Contiguous Area of Kenya

  • S. K. Moloo
Article

Abstract

In south-eastern Uganda the natural hosts of Glossina pallidipes, G. fuscipes fuscipes and G. brevipalpis appear to influence trypanosome infection rates in these vectors. The transmission index of these vectors also differs. Temperature is yet another factor affecting trypanosome infection rates in these tsetses. Other factors probably also form important components in the transmission cycle. In this region of Uganda and its contiguous lake shore area of Kenya there are extant foci of the infections, and man and his symbiotic livestock are exposed to a high challenge of trypanosomiases. Furthermore, in this high endemic/enzootic ecological zone of tropical Africa, the transmission of trypanosome infections to the adventitious hosts, via the tsetse vectors, depends upon a variety of complex interacting factors.

Key Words

Glossina trypanosomiasis Kenya Uganda 

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References

  1. Ashcroft M. T. (1959) The importance of African wild animals as reservoirs of trypanosomiasis. East African Med. J. 36, 289–297.Google Scholar
  2. Ashcroft M. T., Burtt E. and Fairbairn H. (1959) The experimental infection of some African wild animals with Trypanosoma rhodesiense, T. brucei and T congolense. Ann. trop. Med. Parasitol. 53, 147–161.CrossRefGoogle Scholar
  3. Bell H. (1909) Report on the measures adopted for the suppression of sleeping sickness in Uganda. Colonial Reports—Miscellaneous, 65, 3–27. H.M.S.O., London.Google Scholar
  4. Boreham P. F. L. and Gill G. S. (1973) Serological identification of reptile feeds of Glossina. Acta Trop. 30, 356–365.PubMedGoogle Scholar
  5. Bruce D., Nabarro D. and Greig E. D. W. (1903) Futher report on sleeping sickness in Uganda. Report of Sleeping Sickness Commission of Royal Society 4, 3.Google Scholar
  6. Burridge M. J., Pullan N. B., Reid H. W., Southerst R. W. and Wain E. B. (1967) A survey of trypanosome infections in wild animals in Busoga, Uganda. East African Trypanosomiases Research Organization Annual Report for 1966, pp. 60–62.Google Scholar
  7. Buxton P. A. (1955) The natural history of tsetse fly. London School of Hygiene and Tropical Medicine Memoir 10. H. K. Lewis, London.Google Scholar
  8. Doyle J. J. (1977) Antigenic variation in the salivarian trypanosomes. Adv. Exp. Med. Biol. 93, 31–63.CrossRefGoogle Scholar
  9. Ford J. and Leggate B. M. (1961) The geographical and climatic distribution of trypanosome infection rates in the G. morsitans group of tsetse flies. Trans. R. Soc. trop. Med. Hyg. 55, 383–397.CrossRefGoogle Scholar
  10. Garnham P. C. C. (1960) Blood parasites of hippopotamus in Uganda. East Afr. Med. J. 37, 495.PubMedGoogle Scholar
  11. Gray A. R. (1965a) Antigenic variation in a strain of Trypanosoma brucei transmitted by Glossina morsitans and G. palpalis. J. gen. Microbiol. 41, 195–214.CrossRefGoogle Scholar
  12. Gray A. R. (1965b) Antigenic variation in clones of Trypanosoma brucei. Ann. trop. Med. Parasitol. 59, 27–36.CrossRefGoogle Scholar
  13. Guilbride P. P. L., Coyle T. J., Mcanulty E. G., Baker L. and Lomax G. D. (1962) Some pathogenic agents found in hippopotamus in Uganda. J. Comp. Pathol. 72, 137–141.CrossRefGoogle Scholar
  14. Harley J. M. B. (1966) Studies on age and trypanosome infection rate in females of Glossina pallidipes Aust, G. palpalis fuscipes Newst. and G. brevipalpis Newst. Bull. Ent. Res. 57, 23–37.CrossRefGoogle Scholar
  15. Harley J. M. B. and Wilson A. J. (1968) Comparison between Glossina morsitans, G. pallidipes and G. fuscipes as vectors of trypanosomes of the Trypanosoma congolense group: the proportions infected experimentally and the numbers of infective organisms extruded during feeding. Ann. trop. Med. Parasitol. 62, 178–187.CrossRefGoogle Scholar
  16. Hornby H. E. (1952) Animal Trypanosomiasis in East Africa, 1949. H.M.S.O., London.Google Scholar
  17. Jordan A. M. (1964) Trypanosome infection rates in Glossina morsitans submorsitans Newst., in Northern Nigeria. Bull. ent. Res. 55, 219–231.CrossRefGoogle Scholar
  18. Jordan A. M. (1965) The hosts of Glossina as the main factor affecting trypanosome infection rates of tsetse flies in Nigeria. Trans. R. Soc. trop. Med. Hyg. 59, 423–431.CrossRefGoogle Scholar
  19. Kinghorn A., Yorke W. and Lloyd L. L. (1913) Final report of the Luangwa Sleeping Sickness Commission of the British South Africa Company 1911–1912. Ann. trop. Med. Parasitol. 7, 183–302.CrossRefGoogle Scholar
  20. Lloyd L. L. and Johnson W. R. (1924) The trypanosome infections of tsetse flies in northern Nigeria and a new method of estimation. Bull. ent. Res. 14, 265–288.Google Scholar
  21. Lumsden W. H. R. (1962) Trypanosomiasis in African wild life. 1st Int. Conf. Wild Life Disease, New York, 24–27 January, 68–88.Google Scholar
  22. Mackichan I. W. (1944) Rhodesian sleeping sickness in. eastern Uganda. Trans. R. Soc. trop. Med. Hyg. 38, 49–60.CrossRefGoogle Scholar
  23. Moloo S. K. (1973) Relationship between hosts and trypanosome infection rates of Glossina swynnertoni Aust. in the Serengeti National Park, Tanzania. Ann. trop. Med. Parasitol. 61, 205–211.CrossRefGoogle Scholar
  24. Moloo S. K. and Kutuza S. B. (1970) Preliminary report on the annual feeding patterns of Glossina. East African Trypanosomiases Research Organization Annual Report for 1970, pp. 33–36.Google Scholar
  25. Moloo S. K. and Kutuza S. B. (1974) Sleeping Sickness survey in Musoma District, Tanzania: Further study on the vector role of Glossina. Trans. R. Soc. trop. Med. Hyg. 68, 403–409.CrossRefGoogle Scholar
  26. Moloo S. K., Steiger R. F. and Brun R. (1973) Trypanosome infection rates in Glossina swynnertoni and G. pallidipes in Ikoma, Musoma District, Tanzania. Parasitol. 66, 259–267.CrossRefGoogle Scholar
  27. Moloo S. K., Steiger R. F., Brun R. and Boreham P. F. L. (1971) Sleeping Sickness survey in Musoma District, Tanzania. II. The role of Glossina in the transmission of Sleeping Sickness. Acta Trop. 28, 189–205.PubMedGoogle Scholar
  28. Moloo S. K., Kutuza S. B. and Boreham P. F. L. (1979) Studies on Glossina pallidipes, G. fuscipes fuscipes and G. brevipalpis in terms of the epidemiology and epizootiology of trypanosomiases in south-eastern Uganda. Ann. trop. Med. Parasitol. in press.Google Scholar
  29. Nash T. A. M. (1944) A low density of tsetse flies associated with a high incidence of sleeping sickness. Bull. Entomol. Res. 35, 51.CrossRefGoogle Scholar
  30. Nash T. A. M. (1948) Tsetse Flies in British West Africa. H.M.S.O., London.Google Scholar
  31. Onyango R. J. (1969) New concepts in the epidemiology of Rhodesian sleeping sickness. Bull. World Health Org. 41, 815–823.PubMedGoogle Scholar
  32. Onyango R. J., Hoeve K. Van and Raadt P. de (1966) The epidemiology of Trypanosoma rhodesiense sleeping sickness in Alego location, Central Nyanza, Kenya. I. Evidence that cattle may act as reservoir hosts of trypanosomiasis infective to man. Trans. R. Soc. trop. Med. Hyg. 60, 175–182.CrossRefGoogle Scholar
  33. Raadt P. de (1974) Immunity and antigenic variation: clinical observations suggestive of immune phenomena in African trypanosomiasis. In Trypanosomiasis and Leishmaniasis, pp. 199–216. Ciba Foundation Symposium 20 (new series). Associated Scientific Publishers, The Netherlands.Google Scholar
  34. Rogers A., Kenyanjui E. N. and Wiggwah A. K. (1972) A high infection rate of Trypanosoma brucei subgroup in Glossina fuscipes. Parasitology 65, 143–146.CrossRefGoogle Scholar
  35. Sequiera L. A. F. de (1935) Rapport de la mission medicale à la Colonie de Guinée en 1932. Ecole Med. trop., Lisbon.Google Scholar
  36. Silva M. A. de Andrade and daSilva J. Marques (1958) On the incidence of trypanosomiasis in game. International Scientific Committee for Trypanosomiasis Research 7th Meeting, pp. 269–272.Google Scholar
  37. Southon H. A. W. (1963) The hosts of Glossina in South Busoga, Uganda. East African Trypanosomiases Research Organization Annual Report for 1961, pp. 35–37.Google Scholar
  38. Vanderplank F. L. (1947) Seasonal and annual variation in the incidence of trypanosomiasis in game. Ann. Trop. Med. Parasitol. 41, 365–374.CrossRefGoogle Scholar
  39. Weitz B. (1956) Identification of blood meals of bloodsucking arthropods Bull. World Health Org. 15, 473–490.Google Scholar
  40. Weitz B. (1963) The feeding habits of Glossina. Bull. Wld Hlth Org. 28, 711–729.Google Scholar
  41. Wilson A. J., Dar F. K. and Paris J. (1972) A study on the transmission of Salivarian trypanosomes isolated from wild tsetse flies. Trop. Anim. Hlth Prod. 4, 14–22.CrossRefGoogle Scholar
  42. Wilson A. J., Paris J. and Dar F. K. (1975) Maintenance of a herd of breeding cattle in an area of high trypanosome challenge. Trop. Anim. Hlth Prod. 7, 63–71.Google Scholar

Copyright information

© ICIPE 1980

Authors and Affiliations

  • S. K. Moloo
    • 1
  1. 1.International Laboratory for Research on Animal DiseasesNairobiKenya

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