Abstract
Medicinal plants play an important role in human health care. It is estimated that about 25–30% of all drugs are evaluated as therapeutic agents derived from natural products. Research in the pharmaceutical industry has demonstrated that for complex diseases, natural products still represent a valuable source for the production of new chemical compounds, since they possess privileged structures. Among Brazilian biodiversity, “catuaba” is popularly used as a tonic to treat fatigue, stress, impotence, memory deficits, and digestive disorders. Studies show antibacterial, trypanocidal, antioxidant, antiarrhythmic, antidepressant, improvement of memory, anti-inflammatory and antinociceptive activities, as well as phytocosmetic activity in cellulite treatment and in anti-ageing. The Brazilian plants known and used as catuaba are represented by more than twenty different species; however, the plant most commonly found in Brazil as “catuaba” is the species Trichilia catigua A. Juss., Meliaceae. Thus, the aim of this paper is to present a review of T. catigua, with emphasis on biological activities, chemical and analytical development and formulations in order to provide a broader and deeper insight, seeking a herbal medicine and/or phytocosmetic as well as future prospects for commercial exploitation and directions for future studies.
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RL, AASGL, ALS (Ph.D. student), LMK (M.Sc.), GCL wrote and revised the article. JCPM was responsible for the project concept and supervision of the study, as well as the writing and review of the manuscript.
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Longhini, R., Lonni, A.A.S.G., Sereia, A.L. et al. Trichilia catigua: therapeutic and cosmetic values. Rev. Bras. Farmacogn. 27, 254–271 (2017). https://doi.org/10.1016/j.bjp.2016.10.005
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DOI: https://doi.org/10.1016/j.bjp.2016.10.005