Diterpenes and a new benzaldehyde from the mangrove plant Rhizophora mangle

Abstract

This work describes the isolation, by high-speed counter-current chromatography, of the diterpenes manool, jhanol and steviol and the benzaldehyde p-oxy-2-ethylhexyl benzaldehyde from the stilt roots hexane extract of the mangrove plant Rhizophora mangle L., Rhizophoraceae. For this, a non-aqueous biphasic solvent system composed of hexane-acetonitrile-methanol 1:1:0.5 (v/v/v) was applied. As far as we know, only steviol was previously isolated in Rhizophoraceae and this is the first time that p-oxy-2-ethylhexyl benzaldehyde is reported.

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Correspondence to Fernanda N. Costa.

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Authors’ contributions

JNM (undergraduate student) did the compound isolation procedure. FSF (PhD student) contributed in compound identification by NMR and literature search. GRM (PhD student) did NMR experiments. GGL was FNC’s PhD supervisor, where this work started, and contributed to critical reading the manuscript. FNC designed the study, supervised the laboratory work and wrote the manuscript. All the authors have read the final manuscript and approved the submission.

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Martins, J.N., Figueiredo, F.S., Martins, G.R. et al. Diterpenes and a new benzaldehyde from the mangrove plant Rhizophora mangle. Rev. Bras. Farmacogn. 27, 175–178 (2017). https://doi.org/10.1016/j.bjp.2016.10.004

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Keywords

  • Manool
  • Jhanol
  • Steviol
  • p-Oxy-2-ethylhexyl benzaldehyde
  • Rhizophora mangle
  • Rhizophoraceae
  • Counter-current chromatography