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Chemical diversity and biological function of indolediketopiperazines from marine-derived fungi

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Abstract

Natural products from marine-derived fungi have attracted considerable attention in the recent two decades. Indolediketopiperazines are one of the most important classes of marine natural products, mainly discovered from the fungal genera Penicillium, Aspergillus and Eurotium. These compounds span a wide range of chemical structures and bioactivities. This review summarizes 155 indolediketopiperazines that were discovered from marine-derived fungi from 2000 to early 2019 and primarily focuses on their chemical diversity and biological function.

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Acknowledgements

This work was financially supported by the National Natural Science Foundation of China (NSFC Grant Nos. 81673351 and 31330009).

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Authors and Affiliations

  1. Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences and Laboratory of Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266071, China

    Jin Cao & Bin-Gui Wang

  2. University of Chinese Academy of Sciences, Beijing, 100049, China

    Jin Cao

  3. Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, 266071, China

    Bin-Gui Wang

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  1. Jin Cao
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  2. Bin-Gui Wang
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B-GW provided the idea and revised the manuscript. JC contributed in preparing the manuscript.

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Correspondence to Bin-Gui Wang.

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Edited by Chengchao Chen.

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Cao, J., Wang, BG. Chemical diversity and biological function of indolediketopiperazines from marine-derived fungi. Mar Life Sci Technol 2, 31–40 (2020). https://doi.org/10.1007/s42995-019-00023-0

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