Genome constellations of rotavirus a isolated from avian species in Brazil, 2008–2015

A Correction to this article was published on 04 December 2020

This article has been updated


Rotaviruses are members of the family Reoviridae and are a common cause of acute diarrhea in many mammalian and avian species. They are non-enveloped icosahedral particles and their genome comprises 11 segments of double-stranded RNA, which encodes six structural proteins (VP1–4, VP6–7) and six nonstructural proteins (NSP1–6). Genotypes are defined based upon the diversity found in these genes and viral characterization plays a central role on epidemiological studies and prevention. Here we investigate the distribution of Brazilian RVAs genotypes in 8 chicken samples collected between 2008 and 2015 from different regions by RT-PCR, partial (Sanger) nucleotide sequencing and phylogenetic analysis from all rotavirus genes. Although the identified genotypes were typical from avian host species, when analyzed together, they form novel genetic constellations: G19-P[31]-I11-R6-C6-M7-A16-N6-T8-E10-H8 and G19-P[31]-I4-R4-C4-M4-A16-N4-T4-E4-H4. This study highlights that avian rotaviruses are widespread among commercial farms in Brazil, and the co-circulation of at least two different genomic constellations indicates that may present a way bigger genetic variability, that can be increased by the possible transmission events from other birds, lack of specific preventive measures, as well as the different viral evolution mechanisms.

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  • 04 December 2020

    A Correction to this paper has been published: <ExternalRef><RefSource></RefSource><RefTarget Address="10.1007/s42770-020-00407-w" TargetType="DOI"/></ExternalRef>


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This work was supported by the São Paulo Research Foundation (FAPESP)—Grant 2014/13531–7, Brazilian Government, by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brasil (CAPES)—Finance Code PROEX—Grant 1841/2016, and by Swedish Research Council—Project No. 2013–6772.

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Correspondence to Laila A. R. Beserra.

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This study was approved by the Committee on Ethics for Animal Trials of the School of Veterinary Medicine, University of São Paulo, under protocol number 3070/2013.

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Beserra, L.A.R., Barbosa, C.M., Berg, M. et al. Genome constellations of rotavirus a isolated from avian species in Brazil, 2008–2015. Braz J Microbiol 51, 1363–1375 (2020).

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  • Rotavirus
  • Avian
  • Diversity
  • Genotypes
  • Sequence analysis
  • Phylogeny