Skip to main content
SpringerLink
Log in

Hysteroscopic Septum Resection by Monopolar Electrode and Reproductive Outcome in 948 Women with Septate Uterus

  • Surgery
  • Published:
SN Comprehensive Clinical Medicine Aims and scope Submit manuscript

Abstract

The purpose of study is to assess reproductive outcome in patients with septate uterus who have undergone hysteroscopic metroplasty by monopolar resectoscope. Nine hundred forty-eight women with septate uterus who were evaluated for infertility were included in this cohort study. All of them had hysteroscopic septum resection by monopolar resectoscope. They used hormone for 2 months after procedure, and hysterosalpingography was done for evaluating uterine cavity after surgery. The age, cause of infertility, pregnancy rate per cycle, and reproductive performance after surgery were evaluated in intracytoplasmic sperm injection (ICSI), frozen embryo transfer (FET), and intrauterine insemination (IUI) cycles. The mean age of patients in ICSI, FET, and IUI group was 34.78±2.25, 34.25±2.37, and 31.03±1.52, respectively. One hundred forty (23.9%) women in ICSI group and 60 (36.8%) women in frozen embryo transfer group and 42 (20.8%) patients in IUI group got pregnant after procedure. The main factor of infertility in ICSI and FET group was male factor 46.2% and 52%, respectively, while in IUI group, ovulatory factor was 39.9%. There was no uterine perforation in patients. Hysteroscopic metroplasty is a safe, simple, and effective procedure that improve reproductive outcome in infertility patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Nouri K, Ott J, Huber JC, Fischer E-M, Stogbauer L, Tempfer CH. Reproductive outcome after hysteroscopic septoplasty in patients with septate uterus- a retrospective cohort study and systematic review of the literature. Reprod Biol Endocrinol. 2010;8:52.

    Article  Google Scholar 

  2. Grimbizis GF, Camus M, Tarlatzis BC, Bontis JN, Devroey P. Clinical implications of uterine malformations and hysteroscopic treatment result. Hum Reprod Update. 2001;7:161–74.

    Article  CAS  Google Scholar 

  3. Brau P, Grau FV, Pons RM. Is hysterosalpangography able to diagnose all uterine malformations correctly? Eur J Radiol. 2005;53:274–9.

    Google Scholar 

  4. Pabuccu R, Gomel V. Reproductive outcome after hysteroscopic metroplasty in women with septate uterus and otherwise unexplained infertility. Fertil Steril. 2004;81:1675–8.

    Article  Google Scholar 

  5. Sanders B. Uterine factors and infertility. J Reprod Med. 2006;51:169–76.

    PubMed  Google Scholar 

  6. -Sparac V, Kupesic S, Ilijas M, Zodan T, Kurjak A, Histologic architecture and vascularization of hysteroscopically excised intrauterine septa.

  7. Mollo A, De Franciscis P, Colacurci N, Cobellis L, Perino A, Venezia R, Hysteroscopic resection of the septum improves the pregnancy rate of women with unexplained infertility: a prospective controlled trial.

  8. Fedele L, Arcaini L, Parazzini F, Vercellini P, di Nola G. Reproductive prognosis after hysteroscopic metroplasty in 102 women: life table analysis. Fertil Steril. 1993;59:768–72.

    Article  CAS  Google Scholar 

  9. Wang JH, Xu KH, Lin J, Chen XZ. Hysteroscopic septum resection of complete septate uterus with cervical duplication, sparing the double cervix in patients with recurrent spontaneous abortions or infertility. Fertil Steril. 2009;91(6):2643–9.

    Article  Google Scholar 

  10. Jakiel G, Robak-Chołubek D, Przytuła-Piłat M. Two-year study of women with fertility problems following uterine septum hysteroscopic treatment. Ann Univ Mariae Curie Sklodowska. 2004;59(2):65–9.

    Google Scholar 

  11. Saygili-Yilmaz ES, Erman-Akar M, Yilmaz Z. A retrospective study on the reproductive outcome of the septate uterus corrected by hysteroscopic metroplasty. Int J Gynecol Obstet. 2002;78:59–60.

    Article  CAS  Google Scholar 

  12. Kormanyos Z, Molnar BG, Pal A. Removal of a residual portion of a uterine septum in women of advanced reproductive age: obstetric outcome. Hum Reprod. 2006;21:1047–51.

    Article  Google Scholar 

  13. Taylor E, Gomel V. The uterus and fertility. Fertil Steril. 2008;89:1–16.

    Article  Google Scholar 

  14. Bradley LD. Complications in hysteroscopy: prevention, treatment and legal risk. Curr Opin Obstet Gynecol. 2002;14:409–15.

    Article  Google Scholar 

  15. Grynberg M, Gervaise A, Faivre E, Deffieux X, Frydman R, Fernandez H. Treatment of twenty-two patients with complete uterine and vaginal septum. J Minim Invasive Gynecol. 2012;19(1):34–9.

    Article  Google Scholar 

  16. Tehrani Nejad ES, Naderi T, Irani S, Azimi NE. Frequency distribution of pregnancy occurrence in infertile women after diagnostic-surgical hysteroscopy. Iranian J Reprod Med. 2007;5:99–102.

    Google Scholar 

  17. Raga F, Bauset C, Remohi J, Bonilla-Musoles F, Simon C, Pellicer A. Reproductive impact of congenital uterine anomalies. Hum Reprod. 1997;12:2277–81.

    Article  CAS  Google Scholar 

  18. Sentilhes L, Sergent F, Roman H, Verspyck E, Marpeau L. Late complications of operative hysteroscopy: predicting patients at risk of uterine rupture during subsequent pregnancy. Eur J Obstet Gynecol Reprod Biol. 2005;120(2):134–8.

    Article  Google Scholar 

  19. Cararach M, Penella J, Ubeda A, Labatisda R. Hysteroscopic incision of septate uterus: scissors versus resectoscope. Hum Reprod. 1994;9:87–9.

    Article  CAS  Google Scholar 

  20. Guarino S, Incandela S, Maneschi S. Hysteroscopic treatment of uterine septum. Acta Eur Fertil. 1989;20(5):321–5.

    CAS  PubMed  Google Scholar 

  21. Mulayim B, Celik NY, Onalan G, Bagis T, Zeyneloglu HB. Sublingual misoprostol for cervical ripening before diagnostic hysteroscopy in premenopausal women: A randomized, double blind, placebo-controlled trial. Fertil Steril. 2010;93(7):2400–4.

    Article  CAS  Google Scholar 

Download references

Availability of Data and Materials

The data that support the findings of the study are available from the corresponding author in SPSS form upon reasonable request.

Code Availability

Not applicable.

Funding

This study was funded by the Tehran University of Medical Sciences, Iran.

Author information

Authors and Affiliations

  1. Department of Obstetrics & Gynecology & Reproductive Endocrinology of Women Hospital, Tehran University of Medical Sciences, Tehran, Iran

    Fateme Davari Tanha

  2. Department of Obstetrics & Gynecology & Reproductive Endocrinology of Valiasr Hospital, Valiasr Health Research Center, Tehran University of Medical Sciences, Tehran, Iran

    Elham Azimi Nekoo

  3. Department of Endocrinology and Female Infertility, Reproductive Medicine Research Center, Royan Institute, Tehran, Iran

    Ensieh Shahrokh Tehraninejad

  4. Department of Obstetrics & Gynecology, Tehran University of Medical Sciences, Tehran, Iran

    Venus Hajialiakbar

Authors
  1. Fateme Davari Tanha
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Elham Azimi Nekoo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ensieh Shahrokh Tehraninejad
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Venus Hajialiakbar
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

EAN, FDT, and VH developed the original idea and the protocol, abstracted, and prepared the manuscript. EAN and VH participated in the study design and analyzed the data. FDT and EST contributed to the study design and data gathering. All authors read and approved the final manuscript

Corresponding author

Correspondence to Venus Hajialiakbar.

Ethics declarations

Ethics Approval and Consent to Participate

Institutional review board approval was obtained from the ethics committees of Tehran University of Medical Sciences.

Consent for Publication

Written and informed consent was obtained from the patients.

Conflict of Interest

The authors declare no competing interests.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical Collection on Surgery

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tanha, F.D., Nekoo, E.A., Tehraninejad, E.S. et al. Hysteroscopic Septum Resection by Monopolar Electrode and Reproductive Outcome in 948 Women with Septate Uterus. SN Compr. Clin. Med. 3, 1399–1403 (2021). https://doi.org/10.1007/s42399-021-00894-4

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s42399-021-00894-4

Keywords

Search

Navigation