Association of Metabolic Status with the Presence of Urinary Tract Stones Requiring Surgical Intervention

Abstract

According to previous studies, the number of patients with urinary tract stones is increasing. An increase in the prevalence of metabolic syndrome and the aging of society are likely to be associated with this increase. This study aimed to determine the prevalence of markers of metabolic disorders in patients with urinary tract stones. This is a single-center, retrospective, cross-sectional study of 715 patients treated surgically for urinary tract stones. Demographic data, blood test measurements, and computed tomography findings were analyzed, and their incidence compared with the general population. A group receiving a single treatment was compared with a group receiving multiple treatments using chi-square tests and two-sample t tests. The mean age was 60.7 ± 14.1 years, and patients in their 60s formed the largest group. Obesity rate peaked at more than 40% in the 40–60-year-old age group; sarcopenia rate was the highest in patients in their 80s (34.1%). There were no differences in indicators of metabolic syndrome and sarcopenia between single and multiple treatments. Obesity and sarcopenia rates were higher in the patients undergoing surgery for urinary tract stones than in the general Japanese population. The prevalence of these two factors was distributed differently in different age groups (higher rates of obesity in the middle-aged group and higher rates of sarcopenia in the elderly group). It is possible that increased fat mass in the younger age group with age and lower activity and protein consumption has led to sarcopenia in the elderly group.

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Data Availability

Data are available at Saitama Medical University Hospital.

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Affiliations

Authors

Contributions

Conception and design: HY; acquisition of data: SI; analysis and interpretation of data: SI; drafting of the manuscript: SI; critical intellectual revisions: HY and CN; statistical analysis: SI; administrative, technical, or material support: TH; supervision: HA.

Corresponding author

Correspondence to Shun Iwasa.

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This study was approved by the Ethics Committee of Saitama Medical University Hospital. Ethics board approval number is 18154.01. Informed consent was obtained in the form of opt-out.

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Informed consent was obtained in the form of opt-out.

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The authors declare no conflict of interest.

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Iwasa, S., Yanaihara, H., Nishimura, C. et al. Association of Metabolic Status with the Presence of Urinary Tract Stones Requiring Surgical Intervention. SN Compr. Clin. Med. (2021). https://doi.org/10.1007/s42399-021-00773-y

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Keywords

  • Aging
  • Malnutrition
  • Obesity
  • Sarcopenia
  • Urolithiasis