Skip to main content

Advertisement

Log in

Fournier’s Gangrene: Management in a Poor Resource Setting

  • Surgery
  • Published:
SN Comprehensive Clinical Medicine Aims and scope Submit manuscript

Abstract

Fournier’s gangrene is a rapidly progressive necrotizing infection of the external genitalia. We aim to share our clinical experience in the management of this disease. This was a retrospective study with data retrieved from the case note of patients seen with Fournier’s gangrene between January 2013 and April 2019. A total of 23 cases were analysed, who were all men, with a mean age of 47 years. The mean duration before presentation was 8 days. Perianal lesion was the most common aetiological factor occurring in 39% and the most common isolated organism was E. coli. The mean number of debridement was 1.5 while 2 patients required colostomy. The mortality rate was 9% in this study. Despite improvement in clinical care, Fournier’s gangrene remains a potentially fatal condition. Thus, aggressive resuscitation, debridement and judicious antibiotic therapy are required.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Heyns CF, Theron P. Fournier’s gangrene. In: Hohenfellner M, Santucci RA, editors. Emergencies in urology. Germany: Springer; 2007. p. 50–60.

    Chapter  Google Scholar 

  2. Jiménez-Pachecoa A, Arrabal-Poloa MA, Arias-Santiagob S, Arrabal-Martína M, Nogueras-Ocañaa M, et al. Fournier gangrene: description of 37 cases and analysis of associated health care costs. Actas Dermosifiliogr. 2012;103:29–35.

    Article  Google Scholar 

  3. Eke N. Fournier’s gangrene: a review of 1726 cases. Br J Surg. 2000;87(6):718–28.

    Article  CAS  Google Scholar 

  4. Aji SA, Alhassan SU, Ujudud MM. Fournier’s gangrene: experience with management of 46 cases in a tertiary institution. Open Journal of Urology. 2012;2:109–12.

    Article  Google Scholar 

  5. Ghnnam WM. Fournier’s gangrene in Mansoura Egypt: a review of 74 cases. J Postgrad Med. 2008;54(2):106–9.

    Article  CAS  Google Scholar 

  6. Ugwumba FO, Nnabugwu II, Ozoemena OF. Fournier’s gangrene -- analysis of management and outcome in south-eastern Nigeria. S Afr J Surg. 2012;50(1):16–9.

    CAS  PubMed  Google Scholar 

  7. Chalya LP, Igenge JZ, Mabula JB, Simbila S. Fournier’s gangrene at a tertiary health facility in northwestern Tanzania: a single centre experiences with 84 patients. BMC Res Notes. 2015;8:481.

    Article  Google Scholar 

  8. Basoglu M, Ozbey I, Atamanalp SS, Yildirgan M, Aydinli B, et al. Management of Fournier’s gangrene: review of 45 cases. Surg Today. 2007;37(7):558–63. https://doi.org/10.1007/s00595-006-3391-6.

    Article  PubMed  Google Scholar 

  9. Medina JP, Tejido AS, de la Rosa KF, Felip NS, Blanco AM, Leiva GO. Fournier gangrene: evaluation of prognostic factors in 90 patients. Actas Urologicas Espanolas. 2008;32(10):1024–30.

    Article  Google Scholar 

  10. Hollabaugh RS Jr, Dmochowski RR, Hickerson WL, Cox CE. Fournier’s gangrene: therapeutic impact of hyperbaric oxygen. Plast Reconstr Surg. 1998;101(1):94–100.

    Article  Google Scholar 

  11. Benjelloun EB, Souiki T, Yakla N, Ousadden A, Mazaz K, Louchi A, et al. Fournier’s gangrene: our experience with 50 patients and analysis of factors affecting mortality. World Journal of Emergency Surgery. 2013;8(1):13.

    Article  Google Scholar 

  12. Çalışkan S, Özsoy E, Sungur M, Gözdaş HT. Fournier’s gangrene: review of 36 cases. Ulus Travma Acil Cerrahi Derg. 2019;25(5):479–83.

    PubMed  Google Scholar 

  13. Yanar H, Taviloglu K, Ertekin C, Guloglu R, Zorba U, et al. Fournier’s gangrene: risk factors and strategies for management. World J Surg. 2006;30(9):1750–4.

    Article  Google Scholar 

  14. Corman JM, Moody JA. Aronson WJ Fournier’s gangrene in a modern surgical setting: improved survival with aggressive management. BJUI. 1999;84(1):85–8.

    Article  CAS  Google Scholar 

  15. Wetterauer C, Ebbing J, Halla A, Kuehl R, Erb S, Egli A, et al. A contemporary case series of Fournier’s gangrene at a Swiss tertiary care center—can scoring systems accurately predict mortality and morbidity? World Journal of Emergency Surgery. 2018;13(1):25.

    Article  CAS  Google Scholar 

  16. Hejase MJ, Simonin JE, Bihrle R, Coogan CL. Genital Fournier’s gangrene: experience with 38 patients. Urology. 1996;47(5):734–9.

    Article  CAS  Google Scholar 

  17. Tahmaz L, Erdemir F, Kibar Y, Cobar A, Orhan Y. Fournier’s gangrene: report of thirty three cases and a review of the literature. International Journal of Urology. 2006;13:7.

    Article  Google Scholar 

  18. Laor E, Palmer LS, Tolia BM, Reid RE, Winter HI. Outcome prediction in patients with Fournier’s gangrene. J Urol. 1995;154(1):89–92.

    Article  CAS  Google Scholar 

  19. Verma S, Sayana A, Kala S, Rai S. Evaluation of the utility of the Fournier’s gangrene severity index in the management of Fournier’s gangrene in North India: a multicentre retrospective study. J Cutan Aesthet Surg. 2012;5(4):273–6.

    Article  Google Scholar 

  20. Unalp H, Kamer E, Derici H, Atahan K, Balci U, Demirdoven C, et al. Fournier’s gangrene: evaluation of 68 patients and analysis of prognostic variables. J Postgrad Med. 2008;54(2):102–5.

    Article  CAS  Google Scholar 

  21. Arora A, Rege S, Surpam S, Gothwal K, Narwade A. Predicting mortality in Fournier gangrene and validating the Fournier gangrene severity index: our experience with 50 patients in a tertiary care center in India. Urol Int. 2019;102(3):311–8.

    Article  Google Scholar 

  22. Tuncel A, Aydin O, Tekdogan U, Nalcacioglu V, Capar Y, Atan A. Fournier’s gangrene: three years of experience with 20 patients and validity of the Fournier’s gangrene severity index score. Eur Urol. 2006;50(4):838–43.

    Article  Google Scholar 

  23. Luján Marco S, Budía A, Di Capua C, Broseta E, Cruz FJ. Evaluation of a severity score to predict the prognosis of Fournier’s gangrene. BJU Int. 2010;106(3):373–6.

    Article  Google Scholar 

  24. Li C, Zhou X, Liu L-F, Qi F, Chen J-B, Zu X-B. Hyperbaric oxygen therapy as an adjuvant therapy for comprehensive treatment of Fournier’s gangrene. Urol Int. 2015;94(4):453–8.

    Article  CAS  Google Scholar 

  25. Pizzorno R, Bonini F, Donelli A, Stubinski R, Medica M, Carmignani G. Hyperbaric oxygen therapy in the treatment of Fournier’s disease in 11 male patients. J Urol. 1997;158(3):837–40.

    Article  CAS  Google Scholar 

  26. Zagli G, Cianchi G, Degl'Innocenti S, Parodo J, Bonetti L, Prosperi P et al. Treatment of Fournier’s gangrene with combination of vacuum-assisted closure therapy, hyperbaric oxygen therapy, and protective colostomy. Case Reports in Anesthesiology 2011;2011:430983.

    Article  Google Scholar 

  27. Mindrup SR, Kealey GP, Fallon B. Hyperbaric oxygen for the treatment of Fournier’s gangrene. J Urol. 2005;173(6):1975–7.

    Article  Google Scholar 

  28. Ozturk E, Ozguc H, Yilmazlar T. The use of vacuum assisted closure therapy in the management of Fournier’s gangrene. Am J Surg. 2009;197(5):660–5.

    Article  Google Scholar 

  29. Cuccia G, Mucciardi G, Morgia G, d’Alcontres FS, Galì A, Cotrufo S, et al. Vacuum-assisted closure for the treatment of Fournier’s gangrene. Urol Int. 2009;82(4):426–31.

    Article  Google Scholar 

  30. Assenza M, Cozza V, Sacco E, Clementi I, Tarantino B, Passafiume F, et al. VAC (Vacuum Assisted Closure) treatment in Fournier’s gangrene: personal experience and literature review. La Clinica Terapeutica. 2011;162(1):e1–5.

    CAS  PubMed  Google Scholar 

  31. Corcoran AT, Smaldone MC, Gibbons EP, Walsh TJ, Davies BJ. Validation of the Fournier’s gangrene severity index in a large contemporary series. J Urol. 2008;180(3):944–8.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Odusanya Benjamin Olasunkanmi.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

Approval of the ethical committee of General hospital Lagos was obtained. Patient anonymity and confidentiality were maintained at all times.

Informed Consent

Informed consent of patients whose pictures were used in the study was obtained and they were re-assured that no identifying body parts will be shown.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article is part of the Topical Collection on Surgery

Appendix

Appendix

PROFORMA: FOURNIER’S GANGRENE

HOSPITAL NUMBER

AGE

GENDER

DURATION BEFORE PRESENTATION

CLINICAL FEATURES

Scrotal pain

Scrotal swelling

Discharge

Discoloration

Exposure of testis

Fever

Pallor

Dehydration

Heart rate

Respiratory rate

Blood pressure

Hypotension

Size of ulcer

Areas affected

scrotum anterior wallscrotum posterior wall perineum ischiorectal fossa penis anterior abdominal wall others

Presence of perianal lesion

Urethral instrumentation

Urethral stricture

Scrotal trauma

Comorbidities:

Diabetes

If yes duration

Immunosuppression

Others state:

INVESTIGATION RESULT

FBC : PCVWBC DIFF.PLATELETS

ELECTROLYTES UREA AND CREATININE On admission

WOUND SWAB M/C/S

MANAGEMENT

Days before debridement

Debridement bedside or theatre

Average number of debridement

Antibiotics intravenous duration

Oral duration

Sitz bath

Duration before commencing sitz bath

Days on admission

Blood Transfusion yes no

No of pints transfused

Surgical closure

Type of surgical closure

Referral yes or no

Colostomy

Death

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Odusanya, B.O., Saliu, N.A. & Salami, O.A. Fournier’s Gangrene: Management in a Poor Resource Setting. SN Compr. Clin. Med. 2, 209–214 (2020). https://doi.org/10.1007/s42399-020-00226-y

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s42399-020-00226-y

Keywords

Navigation