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Enhanced Adhesion of Mussel-inspired Adhesive through Manipulating Contents of Dopamine Methacrylamide and Molecular Weight of Polymer

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Abstract

The aim of this study is to investigate the effect of the contents of modified 3, 4-dihydroxyphenyl-L-alanine (DOPA), named as dopamine methacrylamide (DMA), on the adhesion of mussel-inspired adhesives in air and water. A series of adhesives, p(DMA-co-MEA), were synthesized by copolymerized DMA and methoxy ethylacrylate (MEA) with the content of DMA from 2 mol.% to 10 mol.%. Results of 1H NMR show that the contents of DMA in all adhesives are near to the theory ratios of DMA in the staring reagents. Adhesives with more than 5 mol.% of DMA appear adhesion, while adhesives with 2 mol. % and 3 mol. % of DMA show almost no adhesion in air and water. Adhesive with 7 mol.% of DMA has the highest molecular weight and adhesion either in air or in water in all adhesives. Adhesion of adhesive is synergistically influenced by the content of DMA, molecular weight and elastic modulus of adhesive. It is because that higher content of DMA would provide more DOPA, which leads to the coordination bond between DOPA and metal ions. It is feasible to develop the mussel-inspired adhesive through incorporating DMA into polymers, which will have potential application in the clinic.

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Acknowledgments

This study is supported by National Basic Research Program of China (973 Program, 2012CB933602), National Natural Science Foundation of China (Grant No. 51372210), Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20130184110023), the Basic Research Foundation Key Project of Sichuan Province (Grant No. 2016JY0011), The Fundamental Research Funds for the Central Universities (Grant No. 2682016YXZT11), and Basic Research Foundation of Leshan (2017).

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Authors and Affiliations

  1. Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China

    Xiong Xiong, Guowei Zhang, Jie Weng & Shuxin Qu

  2. School of Life Science and Engineering, Southwest, Jiaotong University, Chengdu, 610031, China

    Xiong Xiong

  3. College of Environmental Science and Engineering, China West Normal University, Nanchong, 637009, China

    Yumei Liu

  4. Collaboration Innovation Center for Tissue Repair Material Engineering Technology, China West Normal University, Nanchong, 637009, China

    Yumei Liu & Feng Shi

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  1. Xiong Xiong
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  2. Yumei Liu
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  5. Jie Weng
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Correspondence to Shuxin Qu.

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Xiong, X., Liu, Y., Shi, F. et al. Enhanced Adhesion of Mussel-inspired Adhesive through Manipulating Contents of Dopamine Methacrylamide and Molecular Weight of Polymer. J Bionic Eng 15, 461–470 (2018). https://doi.org/10.1007/s42235-018-0037-5

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  • DOI: https://doi.org/10.1007/s42235-018-0037-5

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