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Simple and selective conversion of fructose into HMF using extractive-reaction process in microreactor

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Abstract

An extractive-reaction process for the synthesis of HMF from fructose was implemented in microreactor. Experimental conditions were 10 wt.% fructose in water, MIBK as extracting solvent and HCl as catalyst in a temperature window of 120–160 °C, a MIBK/H2O ratio 1 to 9 and an HCl concentration of 0.25–2 M. The dehydration of fructose to HMF is achieved in less than 40s with a total HMF yield higher than 90% at 150 °C. Aqueous and organic phase spontaneously separate at the outlet of the reactor and HMF is obtained in MIBK with a yield of 80% and a purity of 92%.

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Notes

  1. Productivity is defined as the amount of HMF generated per minute and per reactor’s volume. It is calculated by multipluing the flow rate by the concentration of the fructose and the conversion and dividing by the volume of the reactor.

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Acknowledgements

J. L. gratefully acknowledges financial support by “Institut de Chimie de Lyon” (ICL). Authors would like to thank F. Bornette for technical assistance.

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Authors and Affiliations

  1. Laboratoire de Génie des Procédés Catalytiques, University of Lyon, UMR 5285 CNRS - CPE Lyon -Université Claude Bernard Lyon 1, 43 boulevard du 11 novembre 1918, 69100, Villeurbanne, France

    Janine Lueckgen, Laurent Vanoye, Régis Philippe, Pascal Fongarland, Claude de Bellefon & Alain Favre-Réguillon

  2. Institut de Recherches sur la Catalyse et l’Environnement de Lyon, University of Lyon, UMR 5256 CNRS - Université Claude Bernard Lyon 1, 2 avenue Albert Einstein, 69100, Villeurbanne, France

    Janine Lueckgen & Marion Eternot

  3. Conservatoire National des Arts et Métiers, Equipe Pédagogique Nationale 7, 292 rue Saint Martin, 75003, Paris, France

    Alain Favre-Réguillon

Authors
  1. Janine Lueckgen
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  2. Laurent Vanoye
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  3. Régis Philippe
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  4. Marion Eternot
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  5. Pascal Fongarland
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  6. Claude de Bellefon
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  7. Alain Favre-Réguillon
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Correspondence to Alain Favre-Réguillon.

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Lueckgen, J., Vanoye, L., Philippe, R. et al. Simple and selective conversion of fructose into HMF using extractive-reaction process in microreactor. J Flow Chem 8, 3–9 (2018). https://doi.org/10.1007/s41981-018-0004-7

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  • DOI: https://doi.org/10.1007/s41981-018-0004-7

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