Abstract
Ectodermal dysplasia (ED) is a diverse set of syndromic conditions that are derived from mutations. It affects developmental pathways including communication between the overlaying ectoderm and the underlying mesoderm in embryonic development. The most common form of ED syndromes is referred to as X-linked hypohidrotic ectodermal dysplasia or HED. The HED phenotype includes: (1) hypodontia (missing < 5 teeth); (2) oligodontia (missing six or more teeth); (3) anodontia (missing all teeth); (4) conical- shaped teeth; (5) altered hair growth, distribution, and amount (trichodysplasia); (6) reduced sweating (dyshidrosis); (7) altered mucosal sebaceous function (asteatosis); (8) altered keratin nail formation (onychodysplasia).
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Stanford, C.M. Treatment of syndromic hypodontia in ectodermal dysplasia(s). Clin Dent Rev 2, 20 (2018). https://doi.org/10.1007/s41894-018-0032-6
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DOI: https://doi.org/10.1007/s41894-018-0032-6