Sleep and Biological Rhythms

, Volume 16, Issue 2, pp 231–237 | Cite as

Examining the association between obstructive sleep apnea and cardiometabolic risk factors in the elderly

  • Chen-Jung Wu
  • Tung-Wei Kao
  • Yaw-Wen Chang
  • Wei-Liang Chen
Original Article



Obstructive sleep apnea (OSA) and metabolic syndrome (MetS) are common chronic disorders associated with cardiovascular morbidity and mortality. The goal of our research is to identify the associations between OSA and MetS, including different components of MetS, in adults.


We used data from the 2007–2008 National Health and Nutrition Examination Survey, which included 5909 eligible subjects (2898 men, 3011 women), aged 20 and over, who had undergone a complete medical examination and had self-reported three OSA symptom items. The primary study outcome was possible obstructive sleep apnea (pOSA) and MetS components.


Participants in the pOSA group had significantly more MetS components (p < 0.001). In the group aged ≥ 60 years, there was a stronger relationship between pOSA and MetS components. After additional adjustment, the odds ratios for pOSA among those with 2, 4, and 5 MetS components were 3.11, 3.19, and 4.89, respectively (p < 0.05).


In conclusion, our study indicates that the risk of pOSA is higher in association with increased MetS factors, particularly among the elderly. Leading a healthy lifestyle may help reduce OSA risk in elderly patients with MetS.


Obstructive sleep apnea Metabolic syndrome Visceral obesity Inflammation 



There was no acknowledgement directly for this manuscript.

Author contributions

Chen-Jung Wu contributed to the design of the study, was responsible for the management and retrieval of data, contributed to initial data analysis and interpretation, drafted the initial manuscript. Chen-Jung Wu, Tung-Wei Kao, Yaw-Wen Chang, and Wei-Liang Chen decided upon the data collection methods. Chen-Jung Wu and Wei-Liang Chen were also responsible for the data analysis decisions. Wei-Liang Chen conceptualized and designed the study, supervised all aspects of the study, critically reviewed and revised the manuscript, and approved the final manuscript as submitted. All authors meet the ICMJE criteria for authorship.


The authors received no funding for this work.

Compliance with ethical standards

Conflict of interest

The authors declared that they had no competing interests.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Japanese Society of Sleep Research 2018

Authors and Affiliations

  1. 1.Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital; and School of MedicineNational Defense Medical CenterTaipeiTaiwan
  2. 2.Division of Family Medicine, Department of Community MedicineTaoyuan Armed Forces General HospitalTaoyuanTaiwan
  3. 3.Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital; and School of MedicineNational Defense Medical CenterTaipeiTaiwan
  4. 4.Graduate Institute of Clinical Medicine, College of MedicineNational Taiwan UniversityTaipeiTaiwan
  5. 5.Graduate Institute of Medical SciencesNational Defense Medical CenterTaipeiTaiwan

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