Concomitant Endometrioid Adenocarcinoma of the Uterus and Adult Granulosa Cell Tumor of the Ovary Managed by Minimally Invasive Surgery: A Case Report

  • Dipak Limbachiya
  • Mangirish Anil Kenkre
  • Siddhart Shah
Case Report


Granulosa cell tumors are rare tumors of the ovary and are a low-grade malignancy. They are seen in women of all ages and may secrete estrogen. They are classified as sex cord stromal tumors. Due to their inherent estrogenic property, there is propensity of the endometrium to undergo hyperplasia in 25–50% of cases and develop endometrial cancer in about 5%. We report a case of postmenopausal women with endometrioid adenocarcinoma with granulosa cell tumor managed by minimal invasive surgery.

Case Report

A sixty-two year lady, para one, known case of diabetes mellitus presented with history of postmenopausal bleeding in October 2012. On examination clinically, the uterus was bulky and both fornices appeared free and cervix appeared normal. Ultrasonography of abdomen and pelvis revealed a bulky uterus measuring 6.7 × 4.2 × 5.7 cm with a endometrial thickness of 7 mm. A 3.8 × 3.8 × 3.2 cm mildly bulky ovary was incidentally detected with foci of calcification. Findings were...


Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.


  1. 1.
    Chen LM, Berek JS Ovarian and fallopian tubes. In: Haskell CM, editors. Cancer treatment. 5th ed. Philadelphia, PA: WB Saunders; 2000. p. 900–932.Google Scholar
  2. 2.
    Lee IH, Choi CH, Hong DG, et al. Clinicopathologic characteristics of granulosa cell tumors of the ovary: a multicenter retrospective study. J Gynecol Oncol. 2011;22(3):188–95.CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Siegel R, Ma J, Zou Z, et al. Cancer statistics. CA Cancer J Clin. 2014;64:9–29.CrossRefPubMedGoogle Scholar
  4. 4.
    Kitchener HC, Trimble EL. The endometrial cancer working group of the gynecologic cancer intergroup endometrial cancer state of the science meeting. Int J Gynecol Cancer. 2009;19:134–40.CrossRefPubMedGoogle Scholar
  5. 5.
    Childers JM, Surwit EA. Combined laparoscopic and vaginal surgery for the management of two cases of stage I endometrial cancer. Gynecol Oncol. 1993;51:33–8.CrossRefPubMedGoogle Scholar
  6. 6.
    Holub Z, Jabor A, Bartos P, et al. Laparoscopic surgery for endometrial cancer: long-term results of multicentric study. Eur J Gynaecol Oncol. 2002;23:305–10.PubMedGoogle Scholar
  7. 7.
    Kehoe S, Abu-Rustum N. Transperitoneal laparoscopic pelvic and paraaortic lymphadenectomy in gynecologic cancers. Curr Treat Oncol. 2006;7:93–101.CrossRefGoogle Scholar

Copyright information

© Association of Gynecologic Oncologists of India 2018

Authors and Affiliations

  • Dipak Limbachiya
    • 1
  • Mangirish Anil Kenkre
    • 1
  • Siddhart Shah
    • 1
  1. 1.Eva Women Hospital and Endoscopy CentreAhmedabadIndia

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