Sertoli–Leydig Cell Tumour with Heterologous Element with Rare Mitotic Figure Associated with Multinodular Goitre: A Rare Case of Sex Cord Stromal Tumour of Ovary with Rare Association

  • Meenakshi Gothwal
  • Hemanta Kumar Pradhan
  • Garima Yadav
  • Pratibha Singh
Case Report



Sertoli–Leydig cell tumours are uncommon sex cord stromal tumours of the ovary that often present diagnostic confusion due to the various morphological and histopathological patterns that may be assumed by the tumour.


A 28-year-old female presented with abnormal uterine bleeding and thyromegaly is found to have right adnexal mass with elevated serum testosterone. The mass was diagnosed as a Sertoli–Leydig cell tumour, intermediate differentiation with heterologous elements and focal anaplasia. She was treated with surgical resection followed by adjuvant chemotherapy.


Definitive diagnosis is made by histopathological study with immunohistochemistry. Prognosis is related to the degree of cellular differentiation and to the presence of heterologous elements with stage of disease at the time of diagnosis.


Sertoli leydig cell tumour Sex cord stromal tumour Ovary Prognosis Diagnosis Treatment 


Compliance with Ethical Standards

Conflict of interest

None of the authors have any conflict of interest.


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Copyright information

© Association of Gynecologic Oncologists of India 2017

Authors and Affiliations

  • Meenakshi Gothwal
    • 1
  • Hemanta Kumar Pradhan
    • 1
  • Garima Yadav
    • 1
  • Pratibha Singh
    • 1
  1. 1.Department of Obstetrics and GynaecologyAIIMSJodhpurIndia

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