Prospective Study of Comparison of Clinical [Bedside] Examination Versus Examination Under Anaesthesia in Staging of Carcinoma Cervix at VIMS, Bellary
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(1) To compare the bedside staging method and EUA staging methods for staging cervical cancer. (2) To identify factors that may limit bedside staging method for cervical cancer.
The patients suspected of cervical cancer and scheduled for EUA, biopsy and staging on the theatre list were subjected to bedside staging method on the ward on day 1 and on day 2 same patient subjected for EUA staging method. Clinicians performing the staging as EUA were blinded from the results of the bedside staging method. Findings of bedside are compared with EUA.
The study found a correlation of 0.73, 0.81 and 1.00 for the speculum, bimanual and per rectal examination assessment processes, respectively, during bedside method as compared to the EUA. The sensitivity and accuracy of the speculum examination during bedside staging method were 90 and 70%, respectively, while bimanual examination had sensitivity and accuracy of 68 and 65%, respectively. Overall, the bedside staging method to assign the accurate stage of the cervical cancer had a correlation of 0.929 with the sensitivity, positive predictive value and an accuracy of 87.5, 67 and 64%, respectively.
The sample was insufficient to recommend abandoning the EUA staging method for bedside staging method. The bedside staging method under investigation had a high sensitivity of 87.5%, a positive predictive value of 67% and an accuracy of 64%. However, it was more often associated with over-staging than under-staging. The limitations arising from patient factors were statistically insignificant.
KeywordsBedside examination EUA Staging
We hereby would like to thank Dr. Suman Gaddi Professor and HOD, Department of OBG, Dr. Sreenivasalu the superintendent of VIMS, Dr. Krishna Swamy Director and Principal VIMS, Bellary, to allow us to publish this paper.
Compliance with Ethical Standards
Conflict of interest
All authors declare that we have no conflict of interest.
The study was approved by the institutional ethics committee. All procedures performed in studies involving human participants were in accordance with ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was taken from all participants.
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