EVestG Recordings are Vestibuloacoustic Signals

  • Brian Blakley
  • Abdelbaset Suleiman
  • Grant Rutherford
  • Zahra Moussavi
  • Brian Lithgow
Original Article
  • 8 Downloads

Abstract

A field potential can be defined as the ‘synchronous’ firing of many of vestibuloacoustic nerve fibres. Electrovestibulography has been considered as a method to record and detect vestibuloacoustic signals originating mainly from the vestibular system. A clear picture of the likely acoustic, vestibular or vestibuloacoustic origin and the physiologic basis of these field potentials is lacking. Recordings were conducted on anesthetized Guinea Pigs [ketamine (60 mg/kg) and xylazine (6 mg/kg)] to determine the origin of these minute spontaneous field potentials detected, recorded and averaged during Electrovestibulography recordings. Recordings were made with (1) normal hearing and balance (vestibular function), (2) following cisplatin deafening then (3) following both cisplatin deafening and gentamicin vestibular ablation. The detected minute spontaneous field potentials were determined to be both acoustic and vestibular in origin i.e., vestibuloacoustic. Based on the spontaneous activity of acoustic and vestibular nerve fibers arguments are presented that these field potentials are predominantly vestibular.

Keywords

Vestibular Acoustic EVestG Electrovestibulography 

JEL Classification

I10 C12 

Notes

Acknowledgement

This study was supported by Neural Diagnostics Ltd.

Compliance with Ethical Standards

Conflict of interest

BL has < 0.5% shares in Neural Diagnostics Pty. Ltd. and is part time consultant for them.

Ethical Approval

All procedures performed in studies involving animals were in accordance with the ethical standards of the institution or practice at which the studies were conducted.

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Copyright information

© Taiwanese Society of Biomedical Engineering 2018

Authors and Affiliations

  1. 1.Otalaryngology, Health Sciences CenterWinnipegCanada
  2. 2.Biomedical Engineering ProgramUniversity of ManitobaWinnipegCanada
  3. 3.Electrical & Computer EngineeringUniversity of ManitobaWinnipegCanada
  4. 4.Monash Alfred Psychiatry Research CenterMonash UniversityClaytonAustralia
  5. 5.Riverview Health CenterWinnipegCanada

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