Prevention of Central Line-Associated Bloodstream Infections in Children: Current Challenges and Opportunities


Purpose of Review

No longer are healthcare-acquired conditions considered expected costs of care. Given the lack of randomized controlled trials in children, often we are left with extrapolating from adult literature, recommended prevention bundles, and expert opinion. Additionally, strategies that are considered adjunct to the standard prevention bundles have been examined.

Recent Findings

Here, we review standard central line-associated bloodstream infection (CLABSI) prevention bundles as well as adjunct prevention strategies.


Due to the mortality and morbidity risk, indirect and direct costs, and the inevitable penalties associated with these largely preventable harms, we must reliably implement bundles to avoid these healthcare-acquired infections.

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Correspondence to Allison Whalen.

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Whalen, A., Mack, E.H. Prevention of Central Line-Associated Bloodstream Infections in Children: Current Challenges and Opportunities. Curr Treat Options Peds (2020).

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  • Central line-associated bloodstream infection
  • Quality improvement
  • Healthcare-associated infection