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Epidemiology of Anaphylaxis Induced by Food: Incidence, Trends, Natural History, and Bias

Food anaphylaxis epidemiology

  • Food Allergy (M Fernández-Rivas, Section Editor)
  • Published:
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Abstract

Purpose of the Review

We present an updated information on the epidemiology of food-induced anaphylaxis based on meta-analyses and epidemiology studies published in the last 5 to 10 years. Our review covers incidence, trends, natural history (recurrence and deaths), differences by geographic region, foods involved, and demographic and ethnic distributions.

Recent Findings

Various studies and meta-analyses worldwide report a high frequency of food-induced anaphylaxis in childhood and adolescence and an increase in rates of anaphylaxis managed in health care settings. Major efforts have been made to determine whether the frequency of food anaphylaxis and associated trends is distributed in the same way between countries and ethnic groups (high rates in second-generation immigrants in Western countries).

Summary

Food is the main cause of anaphylaxis in childhood and adolescence, although important methodological problems prevent us from concluding that there has been a true increase in food-related anaphylaxis in the last 15 years. Deaths due to food anaphylaxis are very rare but appear more frequently in adolescence. Publications from Central and South America, Asia, and Africa are needed to complete the picture of food anaphylaxis worldwide.

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References and Recommended Reading

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Allergy Unit, Hospital Universitario Fundación Alcorcón, Alcorcón, Spain

    Maria D. Alonso-Diaz Durana M.D., Ph.D, Ana M. Nieto-Nieto M.D., Ph.D, Ana González-Moreno M.D., Ph.D & Miguel Angel Tejedor-Alonso M.D.

  2. Public Health and Medical Specialties, Faculty of Health Sciences, Rey Juan Carlos University, Avda Atenas 1, Alcorcón, Madrid, 28922, Spain

    Miguel Angel Tejedor-Alonso M.D.

  3. Unidad de Alergia, Hospital Universitario Fundación Alcorcón, Budapest 1, 28922, Alcorcón, Madrid, Spain

    Miguel Angel Tejedor-Alonso M.D.

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Alonso-Diaz Durana, M.D., Nieto-Nieto, A.M., González-Moreno, A. et al. Epidemiology of Anaphylaxis Induced by Food: Incidence, Trends, Natural History, and Bias. Curr Treat Options Allergy 9, 137–156 (2022). https://doi.org/10.1007/s40521-022-00305-6

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