Lessons of Drug Allergy Management Through the World Health Organization’s International Classification of Diseases (ICD)-11
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Purposes of review
In order to introduce the advances and use of the new sub-section addressed to the drug hypersensitivity reactions (DHRs) in the World Health Organizations’ International Classification of Diseases (ICD)-11 revision, we here proposed a used case document and discuss the perspective of this new framework.
We expect that the construction of the new section addressed to DHRs in the ICD-11 will allow the collection of more accurate epidemiological data to support quality management of patients with drug allergies, and better facilitate health care planning to implement public health measures to prevent and reduce the morbidity and mortality attributable to DHRs.
Allergy and hypersensitivity reactions, including DHRs, have never been well classified in the World Health Organization’s (WHO) ICD. The ALLERGY in ICD-11 initiative was launched 6 years ago to have a better representation of these disorders in the ongoing 11th revision of the ICD. It has been supported by six major international allergy academies, and collaboration with the WHO has been established and is ongoing so far. This document intends to present advances and use of the new “Drug hypersensitivity” section of the ICD-11.
KeywordsClassification Drug allergy Drug hypersensitivity International Classification of Diseases World Health Organization
drug hypersensitivity reaction
ear, nose, throat
International Classification of Diseases
non-steroidal anti-inflammatory drugs
World Health Organization
We are extremely grateful to all the representatives of the ICD-11 Revision Project with whom we have been carrying on fruitful discussions, helping us to refine the classification presented here: Robert Jakob, Linda Best, Nenad Kostanjsek, Robert J G Chalmers, Jeffrey Linzer, Linda Edwards, Ségolène Ayme, Bertrand Bellet, Rodney Franklin, Matthew Helbert, August Colenbrander, Satoshi Kashii, Paulo E. C. Dantas, Christine Graham, Ashley Behrens, Julie Rust, Megan Cumerlato, Tsutomu Suzuki, Mitsuko Kondo, Hajime Takizawa, Nobuoki Kohno, Soichiro Miura, Nan Tajima, and Toshio Ogawa.
Joint Allergy Academies: American Academy of Allergy Asthma and Immunology (AAAAI), European Academy of Allergy and Clinical Immunology (EAACI), World Allergy Organization (WAO), American College of Allergy Asthma and Immunology (ACAAI), Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI), and Latin American Society of Allergy, Asthma and Immunology (SLAAI).
Luciana Kase Tanno and Pascal Demoly contributed to the construction of the document (designed the study, analyzed and interpreted the data, and wrote the manuscript).
Compliance with ethical standards
Conflict of interest
Luciana Kase Tanno declares that he has no conflict of interest.
Pascal Demoly declares that he has no conflicts of interest.
Human and animal rights and informed consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
References and recommended reading
Papers of particular interest, published recently, have been highlighted as: • Of importance, •• Of major importance
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