Opinion Statement
House dust mite (HDM) sensitization plays a major role in allergic rhinitis and asthma worldwide. Sublingual immunotherapy (SLIT) in its various formulations has been increasingly utilized for the treatment of these conditions in the past several years. HDM-SLIT tablets have been recently introduced with three formulations currently under investigation. SLIT tablets offer the advantage of a more standardized dose than liquid SLIT products. Several studies suggest that HDM-SLIT tablets may be safe and effective in the treatment of allergic rhinitis and asthma in adults, though further investigations will be necessary to fully establish their use in adults and especially in children. The use of HDM-SLIT tablets appears to be very promising and can usher in a new era to potentially stop the “allergic march” from HDM sensitization in early life to the development of asthma.
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Dr. Robert K. Bush receives royalties from UpToDate and is a section editor for Current Opinions in Allergy and Immunology and Current Allergy and Asthma Reports.
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This article is part of the Topical Collection on Specific Immunotherapy
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Bush, R.K. Dust Mite Tablet Immunotherapy: How Does It Compare and Where Does It Fit?. Curr Treat Options Allergy 4, 14–21 (2017). https://doi.org/10.1007/s40521-017-0114-8
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DOI: https://doi.org/10.1007/s40521-017-0114-8