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Caruso C (ed) (2019) Centenarians. An example of positive biology. Springer, Cham. https://doi.org/10.1007/978-3-030-20762-5
Accardi G, Aprile S, Candore G et al (2019) Genotypic and phenotypic aspects of longevity: results from a sicilian survey and implication for the prevention and treatment of age-related diseases. Curr Pharm Des 25:228–235. https://doi.org/10.2174/1381612825666190313115233
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The original work was supported by 20157ATSLF project (Discovery of molecular, and genetic/epigenetic signatures underlying resistance to age-related diseases and comorbidities), granted by the Italian Ministry of Education, University and Research to C.C. and G.C.
Conflict of interest
The authors declare that they have no conflict of interest.
The Institutional Ethics Committee (“Paolo Giaccone”, University Hospital) approved the DESIGN study protocol (Nutrition and Longevity, No. 032017). The study was conducted in accordance with the Declaration of Helsinki and its amendments.
Statement of human and animal rights
All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from the centenarian assisted by her daughter.
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Electronic supplementary material
Below is the link to the electronic supplementary material where oxidative and inflammatory markers of CC are compared with that of the different age groups of female population studied in the DESIGN project.
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Aiello, A., Accardi, G., Aprile, S. et al. Pro-inflammatory status is not a limit for longevity: case report of a Sicilian centenarian. Aging Clin Exp Res (2020). https://doi.org/10.1007/s40520-020-01628-7