Pro-inflammatory status is not a limit for longevity: case report of a Sicilian centenarian

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References

  1. 1.

    Caruso C (ed) (2019) Centenarians. An example of positive biology. Springer, Cham. https://doi.org/10.1007/978-3-030-20762-5

    Google Scholar 

  2. 2.

    Accardi G, Aprile S, Candore G et al (2019) Genotypic and phenotypic aspects of longevity: results from a sicilian survey and implication for the prevention and treatment of age-related diseases. Curr Pharm Des 25:228–235. https://doi.org/10.2174/1381612825666190313115233

    CAS  Article  PubMed  Google Scholar 

  3. 3.

    Accardi G, Aiello A, Aprile S et al (2020) The phenotypic characterization of the cammalleri sisters, an example of exceptional longevity. Rejuvenation Res. https://doi.org/10.1089/rej.2019.2299

    Article  PubMed  Google Scholar 

  4. 4.

    Cammarata G, Duro G, Di Chiara T et al (2019) Circulating miRNAs in successful and unsuccessful aging. A mini-review. Curr Pharm Des 25:4150–4153. https://doi.org/10.2174/1381612825666191119091644

    CAS  Article  PubMed  Google Scholar 

  5. 5.

    Noren Hooten N, Fitzpatrick M, Wood WH 3rd et al (2013) Age-related changes in microRNA levels in serum. Aging (Albany NY) 5:725–740

    Article  Google Scholar 

Download references

Acknowledgements

The original work was supported by 20157ATSLF project (Discovery of molecular, and genetic/epigenetic signatures underlying resistance to age-related diseases and comorbidities), granted by the Italian Ministry of Education, University and Research to C.C. and G.C.

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Correspondence to Calogero Caruso.

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The authors declare that they have no conflict of interest.

Ethical approval

The Institutional Ethics Committee (“Paolo Giaccone”, University Hospital) approved the DESIGN study protocol (Nutrition and Longevity, No. 032017). The study was conducted in accordance with the Declaration of Helsinki and its amendments.

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All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from the centenarian assisted by her daughter.

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Below is the link to the electronic supplementary material where oxidative and inflammatory markers of CC are compared with that of the different age groups of female population studied in the DESIGN project.

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Aiello, A., Accardi, G., Aprile, S. et al. Pro-inflammatory status is not a limit for longevity: case report of a Sicilian centenarian. Aging Clin Exp Res (2020). https://doi.org/10.1007/s40520-020-01628-7

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