Supplemented amino acids may enhance the walking recovery of elderly subjects after hip fracture surgery
The purpose of this study was to investigate whether supplemented essential amino acids (EAAs) could enhance rehabilitation therapy (Rehab) for recovery of walking capacity in subjects after hip fracture surgery (HFS). Eighty-three elderly subjects with HFS (20 ± 11 days after acute trauma) were eligible for the study and randomized to receive Rehab only (Rehab; n = 27), Rehab + placebo (RP; n = 28) or Rehab + EAAs (RE 8 g/day; n = 28). The patients’ walking capacity (m) was measured by 6-min walking distance (6MWD) at admission and at discharge (median 66 days after admission). All patient groups were treated with the same Rehab (2 sessions/day × 5 days/week). The results showed that the gain in 6MWD was higher in RE than in Rehab and RP (p = 0.034; p = 0.024). The study shows that EAA supplementation can enhance walking recovery rate in subjects with HFS.
KeywordsHip fracture Amino acids Walking test
The authors would like to thank Prof. Robert Coates (Centro Linguistico, Bocconi University, P. zale Sarfatti, Milano, Italy), medical writer and editor, for his linguistic revision.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
The study was approved by the scientific ethics committee of the institute (Direzione Generale/Atti/2008/FF/R002/13.2.2008).
All subjects gave their informed written consent.