Inpatient weight curve trajectory as a prognostic factor among adolescents with anorexia nervosa: a preliminary report
- 272 Downloads
To investigate the predictive value of weight restoration trajectories for relapse within the first year after discharge from inpatient treatment among adolescents with AN.
Forty four inpatient adolescents (5 boys, 39 girls) aged 11–18 (M 14.85, SD 1.87) diagnosed with anorexia were assessed at admission and discharge from a general hospital inpatient ward. Re-hospitalizations within 1 year of discharge were recorded. Factors assessed included 1/BMI at admission, 2/BMI at discharge, 3/percent from target weight (PFTW) at discharge, 4/length of hospitalization, and 5/a weight restoration trajectory measuring weight drops during inpatient weight restoration (rates of negative cubic variation in body weight (NCV).
Logistic regression indicated that negative cubic variation rates (NCV) predicted re-hospitalization. PFTW was found only marginally significant.
Variations in weight restoration during inpatient treatment may be used to identify patients at risk for relapse. NCV can alert clinicians to initiate early relapse prevention interventions before discharge.
Level of Evidence Level III, cohort study.
KeywordsEating disorders Inpatient treatment Adolescents Weight restoration Weight curve
Compliance with ethical standards
Conflict of interest
On behalf of all authors, the corresponding author states that there is no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the official IRB Committee of the hospital and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
- 14.Gross G, Russell JD, Beumont PJV, Touyz SW, Roach P, Aslani A, Allen BJ (2000) Longitudinal study of patients with anorexia nervosa 6 to 10 years after treatment: impact of adequate weight restoration on outcome. Ann NY Acad Sci 904:614–616. doi: 10.1111/j.1749-6632.2000.tb06525.x CrossRefPubMedGoogle Scholar
- 15.Hertman I, Brunstein-Klomek A, Goldzweig G, Hadas A, Horwitz M, Fennig S (2016) Percentage from target weight (PFTW) predict re-hospitaliztion in adolescent anorexia nervosa. Isr J Psychiatry Relat Sci. (in Press) Google Scholar
- 23.Remschmidt H, Müller HG (1987) Stationäre gewichts-ausgangsdaten und langzeitprognose der Anorexia nervosa. [Changes in weight during inpatient treatment and long-term outcome in anorexia nervosa.] Zeitschrift für Kinder-und Jugendpsychiatrie und Psychotherapie.Google Scholar
- 30.Wales J, Brewin N, Cashmore R, Haycraft E, Baggott J, Cooper A, Arcelus J (2016) Predictors of positive treatment outcome in people with anorexia nervosa treated in a specialized inpatient unit: the role of early response to treatment. Eur Eat Disord Rev 24:417–424. doi: 10.1002/erv.2443 CrossRefPubMedGoogle Scholar