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New Technologies for Prevention of Catheter Associated Urinary Tract Infection

  • New Technologies and Advances in Infection Prevention (A Marr, Section Editor)
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Opinion statement

Catheter-associated urinary tract infection (CAUTI) is one of the most common nosocomial infections. Patients with indwelling urinary catheters (IUC) for more than a month are sure to develop bacteriuria. Bacteria form biofilms on IUC, and encrustations develop due to deposition of mineral salts. Together, these block the flow of urine through the catheter and cause severe complications. Completely avoiding the use of urinary catheters is not always possible for certain patients. Systemic use of antibiotics has not been successful in controlling these infections. Coating the urinary catheters with various antibacterial materials is studied as a way to control the development of biofilm and thus infection. Several engineering innovations have also been reported to control CAUTI. Various management measures are also helpful in preventing CAUTI. Here, we review a number of novel coatings and engineering strategies that have been reported to be effective against CAUTI. These technologies can be developed, either individually or in combination, as safety mechanisms against CAUTI.

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References and Recommended Reading

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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  1. Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 1E, Kent Ridge Road, NUHS Tower Block, Level 10, Singapore, 119228, Singapore

    Kedar Diwakar Mandakhalikar MVSc, AH, Rongyuan Ray Chua PhD & Paul Anantharajah Tambyah MBBS, MD

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Dr. Tambyah declares grants from Sanofi-Pasteur, Fabentech and GSK, and Honoraria from Johnson and Johnson.

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Mandakhalikar, K.D., Chua, R.R. & Tambyah, P.A. New Technologies for Prevention of Catheter Associated Urinary Tract Infection. Curr Treat Options Infect Dis 8, 24–41 (2016). https://doi.org/10.1007/s40506-016-0069-5

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