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Aging, Mastication, and Malnutrition and Their Associations with Cognitive Disorder: Evidence from Epidemiological Data

  • Oral Disease and Nutrition (F Nishimura, Section Editor)
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Abstract

Purpose of Review

As the world’s population ages, the decline of cognitive function and dementia among elderly people are becoming serious problems. Cognitive impairment and dementia affect the quality of life and increase health care costs. Possible risk factors for cognitive impairment and dementia include masticatory dysfunction and malnutrition. Recent findings in epidemiological studies in which the associations of mastication and malnutrition with cognitive disorders in elderly people were investigated are described in this review.

Recent Findings

There have been several longitudinal studies and many cross-sectional studies on these associations. Many studies showed that mastication directly affected cognitive function. Furthermore, mastication has been interrelated to nutritional status, which affects cognitive function.

Summary

Most studies have shown positive associations of them in elderly people. Mastication and the status of nutrition might both affect cognitive function while related to each other.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Association, A.s. 2016 Alzheimer’s disease facts and figures. Alzheimers Dement. 2016;12(4):459–509.

    Article  Google Scholar 

  2. Hugo J, Ganguli M. Dementia and cognitive impairment: epidemiology, diagnosis, and treatment. Clin Geriatr Med. 2014;30(3):421–42.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Lamy M, Mojon P, Kalykakis G, Legrand R, Butz-Jorgensen E. Oral status and nutrition in the institutionalized elderly. J Dent. 1999;27(6):443–8.

    Article  CAS  PubMed  Google Scholar 

  4. Wakai K, Naito M, Naito T, Kojima M, Nakagaki H, Umemura O, et al. Tooth loss and intakes of nutrients and foods: a nationwide survey of Japanese dentists. Community Dent Oral Epidemiol. 2010;38(1):43–9.

    Article  PubMed  Google Scholar 

  5. Weijenberg RA, et al. Two-colour chewing gum mixing ability: digitalisation and spatial heterogeneity analysis. J Oral Rehabil. 2013;40(10):737–43.

    CAS  PubMed  Google Scholar 

  6. Kamiyama M, Kanazawa M, Fujinami Y, Minakuchi S. Validity and reliability of a self-implementable method to evaluate masticatory performance: use of color-changeable chewing gum and a color scale. J Prosthodont Res. 2010;54(1):24–8.

    Article  PubMed  Google Scholar 

  7. Ueno M, et al. Masticatory ability and functional tooth units in Japanese adults. J Oral Rehabil. 2008;35(5):337–44.

    Article  CAS  PubMed  Google Scholar 

  8. Saito S, Ohi T, Murakami T, Komiyama T, Miyoshi Y, Endo K, et al. Association between tooth loss and cognitive impairment in community-dwelling older Japanese adults: a 4-year prospective cohort study from the Ohasama study. BMC Oral Health. 2018;18(1):142.

    Article  PubMed  PubMed Central  Google Scholar 

  9. • Hatta K, et al. Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese people in a 3-year prospective study. Geriatr Gerontol Int. 2018;18(10):1439–46 Oral examination was performed by objective evaluation, and investigation was carried out to determine which of the factors of posterior occlusal support, number of teeth, and periodontal disease is most strongly associated with cognitive functions among the evaluations of oral conditions.

    Article  PubMed  Google Scholar 

  10. Li J, Xu H, Pan W, Wu B. Association between tooth loss and cognitive decline: a 13-year longitudinal study of Chinese older adults. PLoS One. 2017;12(2):e0171404.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  11. Tsakos G, Watt RG, Rouxel PL, de Oliveira C, Demakakos P. Tooth loss associated with physical and cognitive decline in older adults. J Am Geriatr Soc. 2015;63(1):91–9.

    Article  PubMed  Google Scholar 

  12. •• Naorungroj S, Schoenbach VJ, Wruck L, Mosley TH, Gottesman RF, Alonso A, et al. Tooth loss, periodontal disease, and cognitive decline in the Atherosclerosis Risk in Communities (ARIC) study. Community Dent Oral Epidemiol. 2015;43(1):47–57 Oral examination was performed by objective evaluation (not self-reported), and multiple evaluations of cognitive functions were performed. Both the number of subjects and the follow-up period were sufficient.

    Article  PubMed  Google Scholar 

  13. •• Takeuchi K, et al. Tooth loss and risk of dementia in the community: the Hisayama study. J Am Geriatr Soc. 2017;65(5):e95–e100 Oral examination was performed by objective evaluation, and a sub-analysis was conducted to classify the types of dementia. Both the number of subjects and the follow-up period were sufficient.

    Article  PubMed  Google Scholar 

  14. Stewart R, Stenman U, Hakeberg M, Hägglin C, Gustafson D, Skoog I. Associations between oral health and risk of dementia in a 37-year follow-up study: the prospective population study of women in Gothenburg. J Am Geriatr Soc. 2015;63(1):100–5.

    Article  PubMed  Google Scholar 

  15. • Okamoto N, et al. Association between tooth loss and the development of mild memory impairment in the elderly: the Fujiwara-kyo study. J Alzheimers Dis. 2015;44(3):777–86 Both the number of subjects and the follow-up period were sufficient.

    Article  PubMed  Google Scholar 

  16. Shin MS, et al. Rehabilitation of lost teeth related to maintenance of cognitive function. Oral Dis. 2018.

  17. Okubo H, et al. Hardness of the habitual diet and its relationship with cognitive function among 70-year-old Japanese elderly: findings from the SONIC study. J Oral Rehabil. 2018.

  18. Nilsson H, Berglund JS, Renvert S. Periodontitis, tooth loss and cognitive functions among older adults. Clin Oral Investig. 2018;22(5):2103–9.

    Article  PubMed  Google Scholar 

  19. Cocco F, Campus G, Strohmenger L, Ardizzone VC, Cagetti MG. The burden of tooth loss in Italian elderly population living in nursing homes. BMC Geriatr. 2018;18(1):76.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Park K, Hong GS. Predictors of chewing ability among community-residing older adults in Korea. Geriatr Gerontol Int. 2017;17(1):78–84.

    Article  PubMed  Google Scholar 

  21. Kim EK, Lee SK, Choi YH, Tanaka M, Hirotsu K, Kim HC, et al. Relationship between chewing ability and cognitive impairment in the rural elderly. Arch Gerontol Geriatr. 2017;70:209–13.

    Article  PubMed  Google Scholar 

  22. Zhu J, Li X, Zhu F, Chen L, Zhang C, McGrath C, et al. Multiple tooth loss is associated with vascular cognitive impairment in subjects with acute ischemic stroke. J Periodontal Res. 2015;50(5):683–8.

    Article  CAS  PubMed  Google Scholar 

  23. Weijenberg RA, et al. Oral mixing ability and cognition in elderly persons with dementia: a cross-sectional study. J Oral Rehabil. 2015;42(7):481–6.

    Article  CAS  PubMed  Google Scholar 

  24. Takeuchi K, Izumi M, Furuta M, Takeshita T, Shibata Y, Kageyama S, et al. Posterior teeth occlusion associated with cognitive function in nursing home older residents: a cross-sectional observational study. PLoS One. 2015;10(10):e0141737.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  25. Iwasaki M, Kimura Y, Yoshihara A, Ogawa H, Yamaga T, Sato M, et al. Oral health status in relation to cognitive function among older Japanese. Clin Exp Dent Res. 2015;1(1):3–9.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Cerutti-Kopplin D, Emami E, Hilgert JB, Hugo FN, Padilha DMP. Cognitive status of edentate elders wearing complete denture: does quality of denture matter? J Dent. 2015;43(9):1071–5.

    Article  PubMed  Google Scholar 

  27. Koyanagi A, Lara E, Stubbs B, Carvalho AF, Oh H, Stickley A, et al. Chronic physical conditions, multimorbidity, and mild cognitive impairment in low- and middle-income countries. J Am Geriatr Soc. 2018;66(4):721–7.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Guigoz Y. The Mini Nutritional Assessment (MNA) review of the literature--what does it tell us? J Nutr Health Aging. 2006;10(6):466–85 discussion 485-7.

    CAS  PubMed  Google Scholar 

  29. Salva A, et al. Nutritional assessment of residents in long-term care facilities (LTCFs): recommendations of the task force on nutrition and ageing of the IAGG European region and the IANA. J Nutr Health Aging. 2009;13(6):475–83.

    Article  CAS  PubMed  Google Scholar 

  30. Vellas B, Guigoz Y, Garry PJ, Nourhashemi F, Bennahum D, Lauque S, et al. The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition. 1999;15(2):116–22.

    Article  CAS  PubMed  Google Scholar 

  31. Rubenstein LZ, Harker JO, Salva A, Guigoz Y, Vellas B. Screening for undernutrition in geriatric practice: developing the short-form mini-nutritional assessment (MNA-SF). J Gerontol A Biol Sci Med Sci. 2001;56(6):M366–72.

    Article  CAS  PubMed  Google Scholar 

  32. van Stijn MF, et al. Preoperative nutrition status and postoperative outcome in elderly general surgery patients: a systematic review. JPEN J Parenter Enteral Nutr. 2013;37(1):37–43.

    Article  PubMed  Google Scholar 

  33. Ogawa S. Nutritional management of older adults with cognitive decline and dementia. Geriatr Gerontol Int. 2014;14(Suppl 2):17–22.

    Article  PubMed  Google Scholar 

  34. Daradkeh G, et al. Nutritional status and cognitive impairment in elderly. Pak J Biol Sci. 2014;17(10):1098–105.

    Article  PubMed  Google Scholar 

  35. Prell T, Perner C. Disease specific aspects of malnutrition in neurogeriatric patients. Front Aging Neurosci. 2018;10:80.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  36. Favaro-Moreira NC, et al. Risk factors for malnutrition in older adults: a systematic review of the literature based on longitudinal data. Adv Nutr. 2016;7(3):507–22.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  37. Li CL, Tung HJ, Yeh MC. Combined effect of eating alone and a poor nutritional status on cognitive decline among older adults in Taiwan. Asia Pac J Clin Nutr. 2018;27(3):686–94.

    CAS  PubMed  Google Scholar 

  38. •• Tchalla AE, Clément JP, Saulnier I, Beaumatin B, Lachal F, Gayot C, et al. Predictors of rapid cognitive decline in patients with mild-to-moderate Alzheimer disease: a prospective cohort study with 12-month follow-up performed in memory clinics. Dement Geriatr Cogn Disord. 2018;45(1–2):56–65 Nutritional status and cognitive functions were assessed by the widely used MNA and MMSE, respectively. It was clearly indicated that the nutritional status at baseline affects subsequent cognitive functions.

    Article  PubMed  Google Scholar 

  39. Sanders C, Behrens S, Schwartz S, Wengreen H, Corcoran CD, Lyketsos CG, et al. Nutritional status is associated with faster cognitive decline and worse functional impairment in the progression of dementia: the Cache County Dementia Progression Study1. J Alzheimers Dis. 2016;52(1):33–42.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Chen LY, Liu LK, Hwang AC, Lin MH, Peng LN, Chen LK, et al. Impact of malnutrition on physical, cognitive function and mortality among older men living in veteran homes by minimum data set: a prospective cohort study in Taiwan. J Nutr Health Aging. 2016;20(1):41–7.

    Article  PubMed  Google Scholar 

  41. • Wang HP, et al. Trajectories of nutritional status and cognitive impairment among older Taiwanese with hip fracture. J Nutr Health Aging. 2017;21(1):38–45 Nutritional status and cognitive functions were assessed by the widely used MNA and MMSE, respectively. The relationship between nutrition trajectory and cognitive function trajectory during the follow-up period was also examined.

    Article  CAS  PubMed  Google Scholar 

  42. •• Bardon L, et al. Predictors of incident malnutrition in older Irish adults from The Irish Longitudinal Study on Ageing (TILDA) cohort- a MaNuEL study. 2018. This study showed that there was a gender difference between cognitive functions and BMI/weight loss in a large number of community-dwelling elderly people.

  43. • O’Shea E, et al. Malnutrition in hospitalised older adults: a multicentre observational study of prevalence, associations and outcomes. J Nutr Health Aging. 2017;21(7):830–6 Among the studies that were reviewed, this is the only study in the influence of dementia on nutritional status.

    Article  PubMed  Google Scholar 

  44. Lannering C, Ernsth Bravell M, Midlöv P, Östgren CJ, Mölstad S. Factors related to falls, weight-loss and pressure ulcers--more insight in risk assessment among nursing home residents. J Clin Nurs. 2016;25(7–8):940–50.

    Article  PubMed  Google Scholar 

  45. Zhao NN, et al. Research on the nutrition and cognition of high-risk stroke groups in community and the relevant factors. Eur Rev Med Pharmacol Sci. 2017;21(23):5408–14.

    PubMed  Google Scholar 

  46. de van der Schueren, M.A., et al. Malnutrition and risk of structural brain changes seen on magnetic resonance imaging in older adults. J Am Geriatr Soc. 2016;64(12):2457–63.

    Article  Google Scholar 

  47. Timmons S, Manning E, Barrett A, Brady NM, Browne V, O’Shea E, et al. Dementia in older people admitted to hospital: a regional multi-hospital observational study of prevalence, associations and case recognition. Age Ageing. 2015;44(6):993–9.

    Article  PubMed  PubMed Central  Google Scholar 

  48. Mantzorou M, Vadikolias K, Pavlidou E, Serdari A, Vasios G, Tryfonos C, et al. Nutritional status is associated with the degree of cognitive impairment and depressive symptoms in a Greek elderly population. Nutr Neurosci. 2018:1–9.

  49. Santos T, et al. Alzheimer’s disease: nutritional status and cognitive aspects associated with disease severity. Nutr Hosp. 2018;35(6):1298–304.

    Article  PubMed  Google Scholar 

  50. Rocaspana-Garcia M, et al. Study of community-living Alzheimer’s patients’ adherence to the Mediterranean diet and risks of malnutrition at different disease stages. PeerJ. 2018;6:e5150.

    Article  PubMed  PubMed Central  Google Scholar 

  51. Arjuna T, Soenen S, Hasnawati R, Lange K, Chapman I, Luscombe-Marsh N. A cross-sectional study of nutrient intake and health status among older adults in Yogyakarta Indonesia. Nutrients. 2017;9(11).

    Article  PubMed Central  Google Scholar 

  52. Koyama A, Hashimoto M, Tanaka H, Fujise N, Matsushita M, Miyagawa Y, et al. Malnutrition in Alzheimer’s disease, dementia with Lewy bodies, and frontotemporal lobar degeneration: comparison using serum albumin, Total protein, and hemoglobin level. PLoS One. 2016;11(6):e0157053.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  53. Krzyminska-Siemaszko R, et al. Health status correlates of malnutrition in the polish elderly population - results of the Polsenior study. Eur Rev Med Pharmacol Sci. 2016;20(21):4565–73.

    CAS  PubMed  Google Scholar 

  54. Jun T, Yuan Z. Cross sectional study of nutritional status in older han women. Southeast Asian J Trop Med Public Health. 2016;47(1):92–100.

    PubMed  Google Scholar 

  55. Pilleron S, Jésus P, Desport JC, Mbelesso P, Ndamba-Bandzouzi B, Clément JP, et al. Association between mild cognitive impairment and dementia and undernutrition among elderly people in Central Africa: some results from the EPIDEMCA (Epidemiology of Dementia in Central Africa) programme. Br J Nutr. 2015;114(2):306–15.

    Article  CAS  PubMed  Google Scholar 

  56. Peng LN, Cheng Y, Chen LK, Tung HH, Chu KH, Liang SY. Cognition and social-physiological factors associated with malnutrition in hospitalized older adults in Taiwan. J Nurs Res. 2015;23(1):1–5.

    Article  PubMed  Google Scholar 

  57. Chavarro-Carvajal D, Reyes-Ortiz C, Samper-Ternent R, Arciniegas AJ, Gutierrez CC. Nutritional assessment and factors associated to malnutrition in older adults: a cross-sectional study in Bogota, Colombia. J Aging Health. 2015;27(2):304–19.

    Article  PubMed  Google Scholar 

  58. Shi R, Duan J, Deng Y, Tu Q, Cao Y, Zhang M, et al. Nutritional status of an elderly population in Southwest China: a cross-sectional study based on comprehensive geriatric assessment. J Nutr Health Aging. 2015;19(1):26–32.

    Article  CAS  PubMed  Google Scholar 

  59. Lyngroth AL, Hernes SMS, Madsen BO, Söderhamn U, Grov EK. Nutritional screening of patients at a memory clinic--association between patients' and their relatives’ self-reports. J Clin Nurs. 2016;25(5–6):760–8.

    Article  PubMed  Google Scholar 

  60. Jyvakorpi SK, et al. Low protein and micronutrient intakes in heterogeneous older population samples. Arch Gerontol Geriatr. 2015;61(3):464–71.

    Article  CAS  PubMed  Google Scholar 

  61. Beydoun MA, Hossain S, Fanelli-Kuczmarski MT, Beydoun HA, Canas JA, Evans MK, et al. Vitamin D status and intakes and their association with cognitive trajectory in a longitudinal study of urban adults. J Clin Endocrinol Metab. 2018;103(4):1654–68.

    Article  PubMed  PubMed Central  Google Scholar 

  62. Hogervorst E, Kassam S, Kridawati A, Soni M, Xin X, Shifu X, et al. Nutrition research in cognitive impairment/dementia, with a focus on soya and folate. Proc Nutr Soc. 2017;76(4):437–42.

    Article  CAS  PubMed  Google Scholar 

  63. Moore K, Hughes CF, Ward M, Hoey L, McNulty H. Diet, nutrition and the ageing brain: current evidence and new directions. Proc Nutr Soc. 2018;77(2):152–63.

    Article  PubMed  Google Scholar 

  64. Canevelli M, Lucchini F, Quarata F, Bruno G, Cesari M. Nutrition and dementia: evidence for preventive approaches? Nutrients. 2016;8(3):144.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  65. Ryuno H, Kamide K, Gondo Y, Nakama C, Oguro R, Kabayama M, et al. Differences in the association between high blood pressure and cognitive functioning among the general Japanese population aged 70 and 80 years: the SONIC study. Hypertens Res. 2016;39(7):557–63.

    Article  PubMed  Google Scholar 

  66. Llewellyn DJ, et al. Serum albumin concentration and cognitive impairment. Curr Alzheimer Res. 2010;7(1):91–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  67. Ng TP, Feng L, Niti M, Yap KB. Albumin, haemoglobin, BMI and cognitive performance in older adults. Age Ageing. 2008;37(4):423–9.

    Article  PubMed  Google Scholar 

  68. Doorduijn AS, et al. Energy and protein intake of Alzheimer’s disease patients compared to cognitively normal controls: systematic review. J Am Med Dir Assoc. 2019;20(1):14–21.

    Article  PubMed  Google Scholar 

  69. Goodwill AM, Szoeke C. A systematic review and meta-analysis of the effect of low vitamin D on cognition. J Am Geriatr Soc. 2017;65(10):2161–8.

    Article  PubMed  Google Scholar 

  70. Sommer I, Griebler U, Kien C, Auer S, Klerings I, Hammer R, et al. Vitamin D deficiency as a risk factor for dementia: a systematic review and meta-analysis. BMC Geriatr. 2017;17(1):16.

    Article  PubMed  PubMed Central  Google Scholar 

  71. Tak AZA, Dayan E, Bulut HT. Evaluation of diffusion tensor imaging changes and neurocognitive effects of asymptomatic vitamin B12 deficiency. Acta Neurol Belg. 2018;118(2):289–96.

    Article  PubMed  Google Scholar 

  72. Langan RC, Goodbred AJ. Vitamin B12 deficiency: recognition and management. Am Fam Physician. 2017;96(6):384–9.

    PubMed  Google Scholar 

  73. Pearson JF, et al. Vitamin C status correlates with markers of metabolic and cognitive health in 50-year-olds: findings of the CHALICE cohort study. Nutrients. 2017;9(8).

    Article  PubMed Central  CAS  Google Scholar 

  74. Araujo JR, et al. Folates and aging: role in mild cognitive impairment, dementia and depression. Ageing Res Rev. 2015;22:9–19.

    Article  CAS  PubMed  Google Scholar 

  75. Sun J, Wen S, Zhou J, Ding S. Association between malnutrition and hyperhomocysteine in Alzheimer’s disease patients and diet intervention of betaine. J Clin Lab Anal. 2017;31(5).

    Article  CAS  Google Scholar 

  76. Hara J, Shankle WR, Barrentine LW, Curole MV. Novel therapy of hyperhomocysteinemia in mild cognitive impairment, Alzheimer’s disease, and other dementing disorders. J Nutr Health Aging. 2016;20(8):825–34.

    Article  CAS  PubMed  Google Scholar 

  77. Ohara T, Doi Y, Ninomiya T, Hirakawa Y, Hata J, Iwaki T, et al. Glucose tolerance status and risk of dementia in the community: the Hisayama study. Neurology. 2011;77(12):1126–34.

    Article  CAS  PubMed  Google Scholar 

  78. Dye L, Boyle NB, Champ C, Lawton C. The relationship between obesity and cognitive health and decline. Proc Nutr Soc. 2017;76(4):443–54.

    Article  PubMed  Google Scholar 

  79. Fitzpatrick AL, et al. Midlife and late-life obesity and the risk of dementia: cardiovascular health study. Arch Neurol. 2009;66(3):336–42.

    Article  PubMed  PubMed Central  Google Scholar 

  80. Iwasaki M, Yoshihara A, Ogawa H, Sato M, Muramatsu K, Watanabe R, et al. Longitudinal association of dentition status with dietary intake in Japanese adults aged 75 to 80 years. J Oral Rehabil. 2016;43(10):737–44.

    Article  CAS  PubMed  Google Scholar 

  81. Andreas Zenthofer A, et al. Prosthetic rehabilitation of edentulism prevents malnutrition in nursing home residents. Int J Prosthodont. 2015;28(2):198–200.

    Article  PubMed  Google Scholar 

  82. Bomfim RA, de Souza LB, Corrente JE. Tooth loss and its relationship with protein intake by elderly Brazilians-a structural equation modelling approach. Gerodontology. 2018;35(1):51–8.

    Article  PubMed  Google Scholar 

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Funding

This study was supported by the Grants-in-Aid for Scientific Research (18K17286) from the Ministry of Education, Science, Sports, and Culture of Japan, Tokyo, Japan. This work was also supported by The Research Funding for Longevity Sciences (29-25) from the National Center for Geriatrics and Gerontology (NCGG), Japan.

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Authors and Affiliations

  1. Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Faculty of Dental Science, Kyushu University, Fukuoka, Japan

    Shino Suma, Michiko Furuta & Yoshihisa Yamashita

  2. Department of Oral Diseases Research, National Center for Geriatrics and Gerontology, 7-430 Morioka-machi, Obu, Aichi, 747-8511, Japan

    Shino Suma & Kenji Matsushita

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  1. Shino Suma
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  2. Michiko Furuta
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Correspondence to Kenji Matsushita.

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Suma, S., Furuta, M., Yamashita, Y. et al. Aging, Mastication, and Malnutrition and Their Associations with Cognitive Disorder: Evidence from Epidemiological Data. Curr Oral Health Rep 6, 89–99 (2019). https://doi.org/10.1007/s40496-019-0220-8

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