Skip to main content

Advertisement

Log in

Periodontal Disease in Women and Men

  • Epidemiology (M Laine, Section Editor)
  • Published:
Current Oral Health Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

This manuscript will present a narrative review of the distribution of periodontitis in women and men based on recent epidemiological studies.

Recent Findings

Large, global, population-based surveys provide continued evidence that a sexual dimorphism in prevalence of periodontitis exists between women and men. Based on included studies, the prevalence of severe periodontitis is greater in men compared to women by between 4.6 to 12.7%. Environmental or behavioral factors that exhibit a sex differential between women and men do not adequately account for the aforementioned observation. A sex dimorphism in host immune response remains a plausible explanation and requires further investigation.

Summary

There is a sexual dimorphism in susceptibility to periodontitis, reflecting a higher prevalence of destructive periodontal disease in men than women.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Kassebaum NJ, Bernabé E, Dahiya M, Bhandari B, Murray CJ, Marcenes W. Global burden of severe periodontitis in 1990–2010: a systematic review and meta-regression. J Dent Res. 2014;93(11):1045–53.

    Article  CAS  Google Scholar 

  2. Tonetti MS, Jepsen S, Jin L, Otomo-Corgel J. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: a call for global action. J Clin Periodontol. 2017;44(5):456–62.

    Article  Google Scholar 

  3. Shiau HJ, Reynolds MA. Sex differences in destructive periodontal disease: a systematic review. J Periodontol. 2010;81(10):1379–89.

    Article  Google Scholar 

  4. • Eke PI, Dye BA, Wei L, Thornton-Evans GO, Genco RJ. Prevalence of periodontitis in adults in the United States: 2009 and 2010. J Dent Res. 2012;91(10):914–20 Represents one of the first national epidemiological surveys utilizing full mouth periodontal examination protocol.

    Article  CAS  Google Scholar 

  5. Eke PI, Wei L, Borgnakke WS, Thornton-Evans G, Zhang X, Lu H, et al. Periodontitis prevalence in adults ≥ 65 years of age, in the USA. Periodontology. 2000. 2016 Oct;72(1):76–95.

    Article  Google Scholar 

  6. Renvert S, Persson RE, Persson GR. Tooth loss and periodontitis in older individuals: results from the Swedish National Study on aging and care. J Periodontol. 2013;84(8):1134–44.

    Article  Google Scholar 

  7. Carasol M, Llodra JC, Fernández-Meseguer A, Bravo M, García-Margallo MT, Calvo-Bonacho E, et al. Periodontal conditions among employed adults in Spain. J Clin Periodontol. 2016;43(7):548–56.

    Article  Google Scholar 

  8. Lorenzo SM, Alvarez R, Andrade E, Piccardo V, Francia A, Massa F, et al. Periodontal conditions and associated factors among adults and the elderly: findings from the first National Oral Health Survey in Uruguay. Cadernos de saude publica. 2015;31:2425–36.

    Article  Google Scholar 

  9. Susin C, Vecchia CF, Oppermann RV, Haugejorden O, Albandar JM. Periodontal attachment loss in an urban population of Brazilian adults: effect of demographic, behavioral, and environmental risk indicators. J Periodontol. 2004;75(7):1033–41.

    Article  Google Scholar 

  10. Torrungruang K, Tamsailom S, Rojanasomsith K, Sutdhibhisal S, Nisapakultorn K, Vanichjakvong O, et al. Risk indicators of periodontal disease in older Thai adults. J Periodontol. 2005;76(4):558–65.

    Article  Google Scholar 

  11. Bouchard P, Boutouyrie P, Mattout C, Bourgeois D. Risk assessment for severe clinical attachment loss in an adult population. J Periodontol. 2006;77(3):479–89.

    Article  CAS  Google Scholar 

  12. Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: framework and proposal of a new classification and case definition. J Periodontol. 2018;89:S159–72.

    Article  Google Scholar 

  13. • Kumar PS. Sex and the subgingival microbiome: do female sex steroids affect periodontal bacteria? Periodontology 2000. 2013;61(1):103–24 An excellent review of previous investigations primarily limited by culture techniques into associations of specific bacteria with oral contraceptives, pregnancy and menstruation.

    Article  Google Scholar 

  14. Shiau HJ, Reynolds MA. Sex differences in destructive periodontal disease: exploring the biologic basis. J Periodontol. 2010;81(11):1505–17.

    Article  Google Scholar 

  15. ter Horst R, Jaeger M, Smeekens SP, Oosting M, Swertz MA, Li Y, et al. Host and environmental factors influencing individual human cytokine responses. Cell. 2016;167(4):1111–24.

    Article  Google Scholar 

  16. Jaillon S, Berthenet K, Garlanda C. Sexual dimorphism in innate immunity. Clin Rev Allergy Immunol. 2017;30:1–4.

    Google Scholar 

  17. Valerio MS, Basilakos DS, Kirkpatrick JE, Chavez M, Hathaway-Schrader J, Herbert BA, et al. Sex-based differential regulation of bacterial-induced bone resorption. J Periodontal Res. 2017;52(3):377–87.

    Article  CAS  Google Scholar 

  18. • Klein SL, Flanagan KL. Sex differences in immune responses. Nat Rev Immunol. 2016;16(10):626 Sex is a biological variable and should be considered in future immunological studies.

    Article  CAS  Google Scholar 

  19. Rinn JL, Snyder M. Sexual dimorphism in mammalian gene expression. Trends Genet. 2005;21(5):298–305.

    Article  CAS  Google Scholar 

  20. Fish EN. The X-files in immunity: sex-based differences predispose immune responses. Nat Rev Immunol. 2008;8(9):737–44.

    Article  CAS  Google Scholar 

  21. Fleming EB, Nguyen D, Afful J, Carrol l MD, Woods PD. Prevalence of daily flossing among adults by selected risk factors for periodontal disease—United States, 2011–2014. J Periodontol 2018 12.

  22. Woelber JP, Bienas H, Fabry G, Silbernagel W, Giesler M, Tennert C, et al. Oral hygiene-related self-efficacy as a predictor of oral hygiene behaviour: a prospective cohort study. J Clin Periodontol. 2015;42(2):142–9.

    Article  Google Scholar 

  23. Guentsch A, Stier C, Raschke GF, Peisker A, Fahmy MD, Kuepper H, et al. Oral health and dental anxiety in a German practice-based sample. Clin Oral Investig. 2017;21(5):1675–80.

    Article  Google Scholar 

  24. Saatchi M, Abtahi M, Mohammadi G, Mirdamadi M, Binandeh ES. The prevalence of dental anxiety and fear in patients referred to Isfahan dental school, Iran. Dental Research Journal. 2015;12(3):248–53.

    PubMed  PubMed Central  Google Scholar 

  25. White AM, Giblin L, Boyd LD. The prevalence of dental anxiety in dental practice settings. American Dental Hygienists’ Association. 2017;91(1):30–4.

    Google Scholar 

  26. Carlsson V, Hakeberg M, Boman UW. Associations between dental anxiety, sense of coherence, oral health-related quality of life and health behaviour–a national Swedish cross-sectional survey. BMC Oral Health. 2015;15(1):100.

    Article  Google Scholar 

  27. • Duan X, Gleason RC, Li F, Hosur KB, Duan X, Huang D, et al. Sex dimorphism in periodontitis in animal models. J Periodontal Res. 2016;51(2):196–202 Continued use of preclinical models such as done by Duan and colleauges is one approach to more clearly elucidate the biologic basis of sex dimorphism in periodontitis.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Harlan J. Shiau.

Ethics declarations

Conflict of Interest

Dr. Shiau has no conflicts of interest to declare.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

This article is part of the Topical Collection on Epidemiology

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Shiau, H.J. Periodontal Disease in Women and Men. Curr Oral Health Rep 5, 250–254 (2018). https://doi.org/10.1007/s40496-018-0195-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40496-018-0195-x

Keywords

Navigation